HitPredict

Interactor 1: MYL9 (P24844)
Myosin regulatory light polypeptide 9 (20 kDa myosin light chain) (LC20) (MLC-2C) (Myosin RLC) (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) (Myosin regulatory light chain MRLC1)
Gene: MYL9

Interactor 2: CC141 (Q6ZP82)
Coiled-coil domain-containing protein 141 (Coiled-coil protein associated with myosin II and DISC1)
Gene: CCDC141

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20956536
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 172 Hs			1 1530
+	Mm
		93725 MYL9_MOUSE (1-172): 7.51e-67: 203: 99.42		CC141_MOUSE (1-1530): 2.87e-104: 368: 72.72
+	Hs
		159549 ML12B_HUMAN (1-172): 6.88e-67: 203: 93.02		MYH9_HUMAN (316-1357): 1.13e-29: 131: 8.36
+	Hs
		624341 MYL9_HUMAN (1-172): 1.16e-66: 202: 100.00		MYH9_HUMAN (316-1357): 1.13e-29: 131: 8.36
+	Hs
		159551 ML12B_HUMAN (1-172): 6.88e-67: 203: 93.02		MYH11_HUMAN (390-1407): 5.57e-29: 129: 9.72
+	Hs
		580614 ML12A_HUMAN (15-172): 5.65e-65: 198: 94.30		MYH9_HUMAN (316-1357): 1.13e-29: 131: 8.36
+	Hs
		580616 ML12A_HUMAN (15-172): 5.65e-65: 198: 94.30		MYH11_HUMAN (390-1407): 5.57e-29: 129: 9.72
+	Hs
		501101 MLRV_HUMAN (9-166): 3.21e-54: 171: 57.23		MYH1_HUMAN (1-917): 1.93e-30: 133: 8.25
+	Hs
		159550 ML12B_HUMAN (1-172): 6.88e-67: 203: 93.02		MYH10_HUMAN (1-524): 5.14e-13: 76.7: 10.12
+	Hs
		624342 MYL9_HUMAN (1-172): 1.16e-66: 202: 100.00		MYH10_HUMAN (1-524): 5.14e-13: 76.7: 10.12
+	Hs
		580615 ML12A_HUMAN (15-172): 5.65e-65: 198: 94.30		MYH10_HUMAN (1-524): 5.14e-13: 76.7: 10.12
+	Mm
		1143166 Q6ZWQ9_MOUSE (1-172): 7.6e-67: 203: 93.61		MYH10_MOUSE (670-1327): 9.23e-11: 69.4: 10.00
+	Ce
		103426 CALM_CAEEL (97-171): 7.52e-16: 72.2: 25.33		G4S034_CAEEL (41-1167): 1.58e-40: 167: 10.59
+	Hs
		484107 CALM3_HUMAN (97-171): 5.89e-16: 72.5: 25.33		SPTB2_HUMAN (103-1235): 4e-38: 159: 12.52
+	Dm
		527090 CALM_DROME (97-171): 8.45e-16: 71.8: 25.33		SPTCA_DROME (325-1149): 1.15e-36: 154: 11.59
+	Hs
		648467 CALL3_HUMAN (32-93): 4.82e-11: 59.3: 25.76		MYH9_HUMAN (316-1357): 1.13e-29: 131: 8.36
+	Dm
		576974 MLR_DROME (3-163): 7.57e-30: 110: 40.61		Q9W053_DROME (1022-1498): 1.1e-12: 75.6: 9.85
+	Hs
		484121 CALM3_HUMAN (97-171): 5.89e-16: 72.5: 25.33		SPTN1_HUMAN (539-1276): 8.81e-11: 69.2: 11.45