HitPredict

Interactor 1: RBY1E (A6NEQ0)
RNA-binding motif protein, Y chromosome, family 1 member E
Gene: RBMY1E

Interactor 2: RBMX (P38159)
RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed]
Gene: RBMX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex GO:0048026 - positive regulation of mRNA splicing, via spliceosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 496 Hs			1 391
+	Hs
		483431 RBY1A_HUMAN (1-496): 7.45e-68: 227: 99.60		RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00
+	Hs
		745179 RBY1F_HUMAN (1-496): 3.22e-67: 226: 98.79		RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00
+	Hs
		483430 RBY1A_HUMAN (1-496): 7.45e-68: 227: 99.60		RBY1A_HUMAN (1-388): 1.58e-33: 132: 49.74
+	Hs
		483440 RBY1A_HUMAN (1-496): 7.45e-68: 227: 99.60		RBY1F_HUMAN (1-388): 2.31e-33: 131: 49.74
+	Hs
		62459 RBY1E_HUMAN (1-496): 8.19e-68: 227: 100.00		RBY1F_HUMAN (1-388): 2.31e-33: 131: 49.74
+	Hs
		1073368 RBY1F_HUMAN (1-496): 3.22e-67: 226: 98.79		RBY1F_HUMAN (1-388): 2.31e-33: 131: 49.74
+	Hs
		483438 RBY1A_HUMAN (1-496): 7.45e-68: 227: 99.60		CIRBP_HUMAN (4-144): 1.3e-31: 119: 46.00
+	Hs
		1047862 RBY1F_HUMAN (1-496): 3.22e-67: 226: 98.79		CIRBP_HUMAN (4-144): 1.3e-31: 119: 46.00
+	Hs
		745180 SAFB1_HUMAN (7-490): 2.47e-44: 169: 15.99		RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00
+	Hs
		745164 SAFB2_HUMAN (6-483): 3.13e-38: 151: 12.75		RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00
+	Hs
		483437 RBY1A_HUMAN (1-496): 7.45e-68: 227: 99.60		RBM3_HUMAN (8-88): 3.03e-15: 74.3: 55.56
+	Hs
		958194 RBY1F_HUMAN (1-496): 3.22e-67: 226: 98.79		RBM3_HUMAN (8-88): 3.03e-15: 74.3: 55.56
+	Hs
		1020262 SAFB1_HUMAN (7-490): 2.47e-44: 169: 15.99		ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27
+	Hs
		1020256 SAFB2_HUMAN (6-483): 3.13e-38: 151: 12.75		ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27
+	At
		98366 RBG7_ARATH (1-84): 5.07e-34: 128: 36.47		F4JVB9_ARATH (4-70): 3.16e-30: 113: 35.82
+	Hs
		1020353 PPIE_HUMAN (10-95): 4.23e-31: 123: 39.08		ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27
+	Hs
		516744 PPIE_HUMAN (10-95): 4.23e-31: 123: 39.08		PABP1_HUMAN (6-93): 1.47e-17: 86.4: 27.27