Interactor 1: RPB1 (P24928)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
Gene: POLR2A

Interactor 2: RPB7 (P62487)
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)
Gene: POLR2G

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 26186194, 26496610, 28514442, 24981860, 33961781, 35271311, 9201987, 37682711, 36652389, 19240132
Identification Methods affinity chromatography technology, pull down, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb1_1~SHS2_Rpb7-N, RNA_pol_Rpb1_2~SHS2_Rpb7-N
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005665 - RNA polymerase II, core complex
GO:0006366 - transcription by RNA polymerase II
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1970
Hs

1 172
+ Bt
+ Hs
+ Sp
+ Sc
+ Hs
+ Hs
+ Sc
+ Hs
+ At
+ Hs
+ At
+ At

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Last updated: 15 Jul 2024