HitPredict

Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	26496610, 21319273
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF-hand_7~Pkinase
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 2472
+	Hs
		625369 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52
+	Hs
		625380 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		DYST_HUMAN (5-2410): 1.41e-35: 152: 10.59
+	Hs
		625446 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		PLEC_HUMAN (16-1253): 4.4e-31: 137: 9.18
+	Hs
		521469 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		ACTN1_HUMAN (1862-2210): 3.16e-11: 71.2: 22.25
+	Hs
		841168 CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00		SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52
+	Hs
		414820 CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90		CENPF_HUMAN (1723-2444): 8.12e-13: 77: 9.28