HitPredict

Interactor 1: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Interactor 2: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	34026424, 23238014
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 425 Hs			1 913
+	Hs
		1043376 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		1043441 WDR5B_HUMAN (92-417): 1.53e-68: 222: 18.54		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		1043562 TBL1R_HUMAN (109-424): 2.86e-60: 205: 16.52		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		1043469 POC1B_HUMAN (2-229): 2.56e-47: 170: 12.45		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		245601 TBL1X_HUMAN (207-424): 3.72e-35: 138: 17.63		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		997714 RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00		CUL4A_HUMAN (161-913): 0: 955: 81.83
+	Hs
		903209 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		1043016 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		CUL4A_HUMAN (161-913): 0: 955: 81.83
+	Hs
		997713 RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		1041672 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		1043085 WDR5B_HUMAN (92-417): 1.53e-68: 222: 18.54		CUL4A_HUMAN (161-913): 0: 955: 81.83
+	Hs
		1043114 POC1B_HUMAN (2-229): 2.56e-47: 170: 12.45		CUL4A_HUMAN (161-913): 0: 955: 81.83
+	Hs
		903208 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		CUL4A_HUMAN (161-913): 0: 955: 81.83
+	At
		186930 MSI1_ARATH (2-210): 3.43e-31: 125: 13.22		CUL4_ARATH (147-913): 0: 919: 55.73
+	Hs
		1041647 TAF5_HUMAN (153-417): 2.83e-46: 172: 15.23		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		1042101 POC1B_HUMAN (2-229): 2.56e-47: 170: 12.45		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		903207 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		1042394 GRWD1_HUMAN (263-425): 3.54e-26: 111: 23.56		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		903206 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		CUL1_HUMAN (213-913): 0: 778: 30.16
+	Hs
		1041172 GRWD1_HUMAN (263-425): 3.54e-26: 111: 23.56		CUL1_HUMAN (213-913): 0: 778: 30.16