HitPredict

Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: SPDE7 (Q495Y7)
Putative speedy protein E7 (Speedy protein E7 pseudogene)
Gene: SPDYE7P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Pkinase~Spy1
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 208
+	Hs
		625518 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		SPDE1_HUMAN (1-208): 1.77e-105: 308: 84.12
+	Hs
		414944 CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90		SPDE7_HUMAN (1-208): 2.2e-115: 329: 100.00
+	Hs
		414999 CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90		SPDE1_HUMAN (1-208): 1.77e-105: 308: 84.12
+	Hs
		63992 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		SPDE4_HUMAN (19-208): 1.21e-83: 249: 67.37
+	Hs
		960311 CDK5_HUMAN (1-292): 1.62e-138: 394: 59.39		SPDE1_HUMAN (1-208): 1.77e-105: 308: 84.12
+	Hs
		64006 CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87		SPDE4_HUMAN (19-208): 1.21e-83: 249: 67.37
+	Hs
		625484 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		SPDYC_HUMAN (48-204): 1.88e-60: 191: 40.13
+	Hs
		63987 CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90		SPDE4_HUMAN (19-208): 1.21e-83: 249: 67.37
+	Hs
		625485 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		SPDYA_HUMAN (6-205): 1.89e-56: 183: 32.04
+	Hs
		64007 CDK5_HUMAN (1-292): 1.62e-138: 394: 59.39		SPDE4_HUMAN (19-208): 1.21e-83: 249: 67.37
+	Xl
		724514 CDK1A_XENLA (1-291): 1.26e-143: 407: 67.12		SPD1A_XENLA (16-204): 6.23e-68: 211: 40.74
+	Xl
		621606 CDK1B_XENLA (1-291): 1.1e-142: 405: 66.78		SPD1A_XENLA (16-204): 6.23e-68: 211: 40.74
+	Hs
		414951 CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90		SPDYC_HUMAN (48-204): 1.88e-60: 191: 40.13
+	Hs
		414952 CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90		SPDYA_HUMAN (6-205): 1.89e-56: 183: 32.04
+	Hs
		960292 CDK5_HUMAN (1-292): 1.62e-138: 394: 59.39		SPDYA_HUMAN (6-205): 1.89e-56: 183: 32.04
+	Hs
		64008 CDK16_HUMAN (1-286): 4.1e-107: 322: 55.40		SPDE4_HUMAN (19-208): 1.21e-83: 249: 67.37
+	Hs
		960374 CDK16_HUMAN (1-286): 4.1e-107: 322: 55.40		SPDYA_HUMAN (6-205): 1.89e-56: 183: 32.04