HitPredict

Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 1025
+	Hs
		415005 CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		415051 CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90		SCAPE_HUMAN (71-937): 4.97e-45: 179: 13.95
+	Hs
		148286 CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Hs
		625176 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		625177 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18
+	Hs
		625446 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96
+	Hs
		960128 CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87		MYH2_HUMAN (122-873): 5.69e-17: 89: 9.31
+	Hs
		522604 CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87		MYH7_HUMAN (101-931): 7.33e-17: 88.6: 10.36
+	Hs
		522542 CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87		MYH1_HUMAN (122-873): 2.75e-15: 83.2: 8.13
+	Hs
		528368 CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87		MYH6_HUMAN (559-1024): 5.56e-13: 75.9: 9.79
+	Hs
		960382 CDK16_HUMAN (1-286): 4.1e-107: 322: 55.40		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		960413 CDK16_HUMAN (1-286): 4.1e-107: 322: 55.40		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		724717 CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		725114 CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00		MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18