HitPredict

Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25852190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 342
+	Hs
		625202 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		LIS1_HUMAN (62-339): 9.49e-75: 238: 16.72
+	Hs
		414806 CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90		LIS1_HUMAN (62-339): 9.49e-75: 238: 16.72
+	Hs
		625543 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		841304 CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		415016 CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Sc
		565470 PHO85_YEAST (3-290): 6.29e-131: 375: 54.88		NLE1_YEAST (210-341): 6.38e-30: 121: 15.00
+	Sc
		565716 PHO85_YEAST (3-290): 6.29e-131: 375: 54.88		COPA_YEAST (131-323): 1.27e-23: 104: 16.81
+	Hs
		841208 CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00		TAF5_HUMAN (178-328): 1.2e-21: 98: 18.42