HitPredict

Interactor 1: PSB2 (P25043)
Proteasome subunit beta type-2 (EC 3.4.25.1) (Macropain subunit PUP1) (Multicatalytic endopeptidase complex subunit PUP1) (Proteasome component PUP1) (Proteinase YSCE subunit PUP1)
Gene: PUP1

Interactor 2: RAD23 (P32628)
UV excision repair protein RAD23
Gene: RAD23

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	9490418, 37968396
Identification Methods	pull down, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 261 Sc			1 398
+	Sc
		675403 PSB5_YEAST (29-221): 2.42e-81: 247: 28.21		RAD23_YEAST (1-398): 8.4e-101: 306: 100.00
+	Hs
		872302 PSB7_HUMAN (1-258): 5.68e-84: 253: 54.75		RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50
+	Hs
		656577 PSB6_HUMAN (22-231): 9.89e-81: 244: 28.77		RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50
+	Hs
		656184 PSA5_HUMAN (3-228): 4.66e-80: 242: 19.92		RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50
+	Hs
		656576 PSB6_HUMAN (22-231): 9.89e-81: 244: 28.77		RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09
+	Hs
		656183 PSA5_HUMAN (3-228): 4.66e-80: 242: 19.92		RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09
+	Hs
		1303496 PSB7_HUMAN (1-258): 5.68e-84: 253: 54.75		UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53
+	Hs
		656660 PSB6_HUMAN (22-231): 9.89e-81: 244: 28.77		UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53
+	Hs
		1303490 PSB7_HUMAN (1-258): 5.68e-84: 253: 54.75		UBQL2_HUMAN (1-373): 8.68e-55: 192: 12.65
+	Hs
		656337 PSA5_HUMAN (3-228): 4.66e-80: 242: 19.92		UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53
+	Hs
		656655 PSB6_HUMAN (22-231): 9.89e-81: 244: 28.77		UBQL2_HUMAN (1-373): 8.68e-55: 192: 12.65
+	Hs
		656327 PSA5_HUMAN (3-228): 4.66e-80: 242: 19.92		UBQL2_HUMAN (1-373): 8.68e-55: 192: 12.65
+	Hs
		656323 PSA5_HUMAN (3-228): 4.66e-80: 242: 19.92		UBQL4_HUMAN (2-373): 1.16e-52: 186: 13.76
+	Dm
		1374384 Q9VUJ1_DROME (2-258): 8.36e-82: 248: 54.09		Q9VWD9_DROME (2-374): 1.81e-47: 171: 13.38
+	Dm
		1278653 PSA5_DROME (3-229): 7.44e-80: 242: 19.67		Q9VWD9_DROME (2-374): 1.81e-47: 171: 13.38
+	Dm
		1178971 Q7K148_DROME (1-237): 2.57e-77: 237: 24.90		Q9VWD9_DROME (2-374): 1.81e-47: 171: 13.38
+	Hs
		924123 PSB7_HUMAN (1-258): 5.68e-84: 253: 54.75		RS27A_HUMAN (2-89): 1.27e-38: 137: 22.73
+	Hs
		656585 PSB6_HUMAN (22-231): 9.89e-81: 244: 28.77		RS27A_HUMAN (2-89): 1.27e-38: 137: 22.73
+	Hs
		656197 PSA5_HUMAN (3-228): 4.66e-80: 242: 19.92		RL40_HUMAN (2-68): 1.02e-16: 77.7: 26.87
+	Hs
		656238 PSA5_HUMAN (3-228): 4.66e-80: 242: 19.92		NEDD8_HUMAN (2-62): 2.68e-15: 72.3: 24.59