HitPredict

Interactor 1: SPTC1 (P25045)
Serine palmitoyltransferase 1 (SPT 1) (SPT1) (EC 2.3.1.50) (Long chain base biosynthesis protein 1)
Gene: LCB1

Interactor 2: SAC1 (P32368)
Phosphatidylinositol-3-phosphatase SAC1 (EC 3.1.3.64) (Phosphatidylinositol-4-phosphate phosphatase) (Recessive suppressor of secretory defect)
Gene: SAC1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.742

The method score is based on:

Property Details
Experiments 20182505, 30529276, 37982431, 37794019, 37968396, 38285738, 23237950
Identification Methods anti tag coimmunoprecipitation, affinity chromatography technology, biochemical
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0090156 - intracellular sphingolipid homeostasis
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 558
Sc

1 623
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024