HitPredict

Interactor 1: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Interactor 2: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	20936779
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2843 Hs			1 1475
+	Hs
		626074 APC_HUMAN (1-2843): 0: 1316: 100.00		RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12
+	Hs
		626224 APC_HUMAN (1-2843): 0: 1316: 100.00		RNF31_HUMAN (545-922): 9.86e-47: 185: 15.72
+	Hs
		626063 APC_HUMAN (1-2843): 0: 1316: 100.00		NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13
+	Hs
		626278 APC_HUMAN (1-2843): 0: 1316: 100.00		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		65038 APC_HUMAN (1-2843): 0: 1316: 100.00		P121C_HUMAN (211-1269): 1.45e-20: 101: 9.16
+	Hs
		626225 APC_HUMAN (1-2843): 0: 1316: 100.00		P121A_HUMAN (102-1074): 5.78e-16: 86: 9.24
+	Hs
		626080 APC_HUMAN (1-2843): 0: 1316: 100.00		NUP98_HUMAN (749-1368): 8.75e-11: 69.1: 12.83
+	Dm
		1361420 Q9VAS9_DROME (215-2432): 2.92e-159: 554: 18.52		TRBID_DROME (654-921): 1.55e-20: 100: 16.23
+	Dm
		1367033 Q9Y1T2_DROME (327-1386): 2.44e-167: 550: 26.85		TRBID_DROME (654-921): 1.55e-20: 100: 16.23
+	Hs
		1303336 MUC4_HUMAN (710-2820): 1.56e-75: 284: 9.45		MUC4_HUMAN (501-1472): 5.34e-23: 109: 10.71
+	Hs
		257716 ANR17_HUMAN (1869-2843): 8.13e-62: 238: 14.08		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		1056827 MDC1_HUMAN (1750-2784): 3.28e-21: 104: 11.74		MDC1_HUMAN (67-796): 3.59e-56: 217: 14.00
+	Hs
		1290102 SRRM2_HUMAN (943-2827): 1.37e-30: 135: 8.96		RNF31_HUMAN (545-922): 9.86e-47: 185: 15.72
+	Hs
		1264771 TITIN_HUMAN (717-2430): 7.06e-29: 130: 7.55		TITIN_HUMAN (92-940): 3.34e-30: 133: 9.98
+	Hs
		1354883 SRRM2_HUMAN (943-2827): 1.37e-30: 135: 8.96		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		654069 MAP4_HUMAN (2119-2724): 1.19e-29: 131: 15.90		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		1264816 TITIN_HUMAN (717-2430): 7.06e-29: 130: 7.55		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		1057011 MDC1_HUMAN (1750-2784): 3.28e-21: 104: 11.74		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		821070 PRC2A_HUMAN (951-2843): 2.17e-19: 98.6: 7.24		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Dm
		113976 M9PB30_DROME (1208-2013): 4.08e-21: 104: 9.83		M9PB30_DROME (77-757): 6.74e-17: 89.5: 9.05