Protein: CADF
Cofilin/actin-depolymerizing factor homolog (Protein D61) (Protein twinstar)

Gene: CADF, tsr
Organism: Drosophila melanogaster
Interactions: 74
UniProt ID: P45594

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0000915 - actomyosin contractile ring assembly
GO:0001736 - establishment of planar polarity
GO:0001737 - establishment of imaginal disc-derived wing hair orientation
GO:0001745 - compound eye morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

534349

ACT5
Actin-87E

1

20

High-throughput

0.656

High

852484

ACT6
Actin, indirect flight muscle

1

20

High-throughput

0.656

High

852507

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.586

High

852526

Q9VMW2
Reticulon-like protein

2

1

High-throughput

0.584

High

852525

Q9VMV9
Reticulon-like protein

2

1

High-throughput

0.570

High

852488

YAP1
Transcriptional coactivator yorkie

1

5

Small-scale

0.552

High

852539

Q9W579
Insomniac, isoform B

1

8

High-throughput

0.508

High

852500

LIMK1
LIM domain kinase 1

1

4

High-throughput

0.492

High

852487

SEM1A
Semaphorin-1A

1

1

High-throughput

0.489

High

197567

PAX6
Paired box protein Pax-6

1

0

High-throughput

0.486

High

852491

Q7JVK6
Translin

1

0

High-throughput

0.486

High

852505

JUPIT
Microtubule-associated protein Jupiter

1

0

High-throughput

0.486

High

852541

FL2D
Pre-mRNA-splicing regulator female-lethal(2)D

1

0

High-throughput

0.486

High

118800

M9NFI9
Neurabin-1

1

4

High-throughput

0.484

High

120631

M9PE01
cyclin-dependent kinase

1

2

High-throughput

0.484

High

852498

Q8I0S6
pantothenate kinase

1

1

High-throughput

0.481

High

852486

DIAP2
Death-associated inhibitor of apoptosis 2

1

1

High-throughput

0.479

High

852493

Q7K4C2
LD46713p

1

1

High-throughput

0.479

High

852496

SCRIB
Protein lap4

1

1

Small-scale

0.479

High

852497

F10A2
Hsc70-interacting protein 2

1

1

High-throughput

0.479

High

852502

NFKB1
Nuclear factor NF-kappa-B p110 subunit

1

3

High-throughput

0.479

High

852512

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

6

High-throughput

0.479

High

852535

PGPLE
Peptidoglycan-recognition protein LE

1

1

High-throughput

0.479

High

356731

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

0

High-throughput

0.464

High

852518

Q9VJW9
ADAM10 endopeptidase

1

0

High-throughput

0.464

High

852521

Q9VLS7
LD21067p

1

0

High-throughput

0.464

High

852543

X2JCC3
poly(A)-specific ribonuclease

1

0

High-throughput

0.464

High

852494

IMD
Protein immune deficiency

1

0

High-throughput

0.458

High

852504

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.458

High

852506

FADD
Fas-associated death domain protein

1

0

High-throughput

0.458

High

852510

Q9VDI1
LD46328p

1

0

High-throughput

0.458

High

852531

PYRG
CTP synthase

1

0

High-throughput

0.458

High

852537

TNG2
Transport and Golgi organization protein 2

1

0

High-throughput

0.458

High

852528

Q9VPG5
pantothenate kinase

1

1

High-throughput

0.457

High

2661

A0A0B4LET0
Uncharacterized protein, isoform B

1

1

High-throughput

0.445

High

90869

F10A1
Hsc70-interacting protein 1

1

1

High-throughput

0.445

High

117955

M9MRJ4
Muscle-specific protein 300 kDa, isoform G

1

4

High-throughput

0.445

High

613924

SGG
Protein kinase shaggy

1

2

High-throughput

0.445

High

852513

BLM
RecQ-like DNA helicase Blm

1

1

High-throughput

0.445

High

852516

Q9VJ30
non-specific serine/threonine protein kinase

1

6

High-throughput

0.445

High

852519

PIWI
Protein piwi

1

1

High-throughput

0.445

High

852540

DRONC
Caspase Dronc

1

1

High-throughput

0.445

High

852485

Q0E8S4
Semaphorin-1A

1

1

High-throughput

0.442

High

852530

SNAPN
SNAPIN protein homolog

1

0

High-throughput

0.438

High

852503

PGPLC
Peptidoglycan-recognition protein LC

1

1

High-throughput

0.437

High

235200

HTH
Homeobox protein homothorax

1

0

High-throughput

0.426

High

604329

CATA
Catalase

1

0

High-throughput

0.426

High

852492

Q7JZT9
allantoinase

1

0

High-throughput

0.426

High

852499

Q8INK3
Fatty acid-binding protein, muscle

1

0

High-throughput

0.426

High

852508

Q9VAC1
GM14349p

1

0

High-throughput

0.426

High

852523

Q9VMH3
LD04103p

1

0

High-throughput

0.426

High

852524

Q9VMM7
FI04466p

1

0

High-throughput

0.426

High

852527

Q9VN21
LD30155p

1

0

High-throughput

0.426

High

852514

Q9VGQ1
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.407

High

852489

SSH
Protein phosphatase Slingshot

1

6

High-throughput

0.381

High

852509

Q9VBR6
RE74917p

2

0

High-throughput

0.298

High

852515

Q9VHM0
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

852520

Q9VKS2
GEO11429p1

1

0

High-throughput

0.265

Low

852483

SDC
Syndecan

1

0

High-throughput

0.253

Low

852536

RT25
Small ribosomal subunit protein mS25

1

0

High-throughput

0.253

Low

356309

O97102
Small ubiquitin-related modifier

1

0

Small-scale

0.249

Low

852490

Q6NQZ7
LD40663p

1

0

High-throughput

0.249

Low

92082

D1Z394
Entomoglyceroporin 4, isoform E

1

0

High-throughput

0.232

Low

852495

Q7KMM5
BcDNA.GH04802

1

0

High-throughput

0.232

Low

852501

Q8SXF0
Small ribosomal subunit protein uS9m

1

0

High-throughput

0.232

Low

852511

Q9VEP4
Uncharacterized protein

1

0

High-throughput

0.232

Low

852517

Q9VJP4
IP01147p

1

0

High-throughput

0.232

Low

852522

Q9VM97
Thrombospondin, isoform A

1

0

High-throughput

0.232

Low

852529

Q9VPU0
Uncharacterized protein

1

0

High-throughput

0.232

Low

852532

Q9VWA0
Uncharacterized protein, isoform C

1

0

High-throughput

0.232

Low

852533

MINY3
Ubiquitin carboxyl-terminal hydrolase MINDY-3 homolog

1

0

High-throughput

0.232

Low

852534

Q9VX17
LD36024p

1

0

High-throughput

0.232

Low

852538

Q9W4X5
Brivido-3, isoform B

1

0

High-throughput

0.232

Low

852542

X2JA38
Tweek, isoform J

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025