HitPredict

Interactor 1: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Interactor 2: SMU1 (Q2TAY7)
WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]
Gene: SMU1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29507117
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2843 Hs			1 513
+	Hs
		1103013 CIC_HUMAN (722-2643): 2.1e-17: 92.4: 7.79		SMU1_HUMAN (1-513): 7.53e-153: 447: 100.00
+	Hs
		1056988 MDC1_HUMAN (1750-2784): 3.28e-21: 104: 11.74		WDR26_HUMAN (3-513): 2.59e-99: 314: 19.45
+	Hs
		793042 SRRM2_HUMAN (943-2827): 1.37e-30: 135: 8.96		LIS1_HUMAN (4-472): 9.67e-90: 282: 15.13
+	Hs
		245652 NCOR2_HUMAN (821-2831): 1.68e-41: 171: 8.41		TBL1X_HUMAN (252-512): 3.08e-62: 215: 18.38
+	Hs
		1309170 NCOR2_HUMAN (821-2831): 1.68e-41: 171: 8.41		TBL1Y_HUMAN (252-512): 1.12e-61: 212: 18.02
+	Hs
		653951 MAP4_HUMAN (2119-2724): 1.19e-29: 131: 15.90		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		820867 PRC2A_HUMAN (951-2843): 2.17e-19: 98.6: 7.24		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		903450 CIC_HUMAN (722-2643): 2.1e-17: 92.4: 7.79		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Mm
		903669 KMT2C_MOUSE (727-2826): 5.47e-17: 90.9: 7.58		WDR5_MOUSE (78-425): 2.83e-76: 245: 21.25
+	Hs
		903374 KMT2C_HUMAN (2340-2838): 4.14e-09: 64.9: 8.02		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		1346974 NCOR2_HUMAN (821-2831): 1.68e-41: 171: 8.41		NLE1_HUMAN (433-513): 1.02e-23: 106: 23.46
+	Hs
		1288413 NCOR2_HUMAN (821-2831): 1.68e-41: 171: 8.41		SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50
+	Hs
		1346970 SRRM2_HUMAN (943-2827): 1.37e-30: 135: 8.96		NLE1_HUMAN (433-513): 1.02e-23: 106: 23.46
+	Hs
		1288394 SRRM2_HUMAN (943-2827): 1.37e-30: 135: 8.96		SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50
+	Hs
		1264784 TITIN_HUMAN (717-2430): 7.06e-29: 130: 7.55		SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50
+	Hs
		1056932 MDC1_HUMAN (1750-2784): 3.28e-21: 104: 11.74		SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50
+	Hs
		929460 MDC1_HUMAN (1750-2784): 3.28e-21: 104: 11.74		RACK1_HUMAN (277-377): 7.24e-11: 65.5: 33.33
+	Hs
		921574 SPEG_HUMAN (1811-2617): 9.45e-10: 67.1: 11.46		GBB2_HUMAN (187-335): 1.43e-21: 97.7: 20.81
+	Hs
		820878 PRC2A_HUMAN (951-2843): 2.17e-19: 98.6: 7.24		RACK1_HUMAN (277-377): 7.24e-11: 65.5: 33.33
+	Hs
		929620 CIC_HUMAN (722-2643): 2.1e-17: 92.4: 7.79		RACK1_HUMAN (277-377): 7.24e-11: 65.5: 33.33