HitPredict

Interactor 1: FPR2 (P25090)
N-formyl peptide receptor 2 (FMLP-related receptor I) (FMLP-R-I) (Formyl peptide receptor-like 1) (HM63) (Lipoxin A4 receptor) (LXA4 receptor) (RFP)
Gene: FPR2

Interactor 2: CERS6 (Q6ZMG9)
Ceramide synthase 6 (CerS6) (LAG1 longevity assurance homolog 6) (Sphingoid base N-palmitoyltransferase CERS6) (EC 2.3.1.291)
Gene: CERS6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006954 - inflammatory response GO:0016020 - membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 351 Hs			1 384
+	Hs
		1168253 CML1_HUMAN (24-348): 9.64e-78: 244: 35.52		CERS6_HUMAN (1-384): 8.88e-163: 463: 100.00
+	Hs
		1030979 GPR17_HUMAN (28-348): 9.78e-77: 242: 22.70		CERS6_HUMAN (1-384): 8.88e-163: 463: 100.00
+	Hs
		814578 P2RY1_HUMAN (29-338): 1.11e-72: 231: 24.61		CERS6_HUMAN (1-384): 8.88e-163: 463: 100.00
+	Hs
		723335 APJ_HUMAN (4-345): 9.85e-70: 224: 24.79		CERS6_HUMAN (1-384): 8.88e-163: 463: 100.00
+	Hs
		626550 FPR2_HUMAN (1-351): 5.96e-75: 236: 100.00		CERS5_HUMAN (6-375): 6.65e-154: 440: 64.96
+	Hs
		849677 CCR6_HUMAN (15-348): 2.3e-65: 212: 24.19		CERS6_HUMAN (1-384): 8.88e-163: 463: 100.00
+	Hs
		674858 AGTR1_HUMAN (16-348): 4.37e-62: 204: 26.98		CERS6_HUMAN (1-384): 8.88e-163: 463: 100.00
+	Hs
		1291792 CML1_HUMAN (24-348): 9.64e-78: 244: 35.52		CERS2_HUMAN (7-342): 1.13e-146: 422: 44.64
+	Hs
		781078 OPRX_HUMAN (22-348): 8.17e-62: 203: 25.60		CERS6_HUMAN (1-384): 8.88e-163: 463: 100.00
+	Hs
		1031047 GPR17_HUMAN (28-348): 9.78e-77: 242: 22.70		CERS2_HUMAN (7-342): 1.13e-146: 422: 44.64
+	Hs
		600824 C5AR1_HUMAN (9-341): 1.37e-75: 238: 32.93		CERS2_HUMAN (7-342): 1.13e-146: 422: 44.64
+	Hs
		600846 C5AR1_HUMAN (9-341): 1.37e-75: 238: 32.93		CERS4_HUMAN (7-370): 1.54e-145: 419: 43.13
+	Hs
		814586 P2RY1_HUMAN (29-338): 1.11e-72: 231: 24.61		CERS2_HUMAN (7-342): 1.13e-146: 422: 44.64
+	Hs
		849683 CCR6_HUMAN (15-348): 2.3e-65: 212: 24.19		CERS5_HUMAN (6-375): 6.65e-154: 440: 64.96
+	Hs
		895677 CXCR4_HUMAN (2-325): 1.65e-62: 204: 27.52		CERS5_HUMAN (6-375): 6.65e-154: 440: 64.96
+	Hs
		781097 OPRX_HUMAN (22-348): 8.17e-62: 203: 25.60		CERS2_HUMAN (7-342): 1.13e-146: 422: 44.64
+	Hs
		1083451 C3AR_HUMAN (196-339): 2.16e-12: 69.7: 33.79		CERS6_HUMAN (1-384): 8.88e-163: 463: 100.00
+	Hs
		1083460 C3AR_HUMAN (196-339): 2.16e-12: 69.7: 33.79		CERS5_HUMAN (6-375): 6.65e-154: 440: 64.96
+	Hs
		1083477 C3AR_HUMAN (196-339): 2.16e-12: 69.7: 33.79		CERS2_HUMAN (7-342): 1.13e-146: 422: 44.64