Interactor 1: ARBK1 (P25098)
Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (EC 2.7.11.15) (G-protein coupled receptor kinase 2)
Gene: GRK2

Interactor 2: GNAQ (P50148)
Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q)
Gene: GNAQ

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.908

The method score is based on:

Property Details
Experiments 10727532, 12885252, 10567430, 21940795
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains G-alpha~RGS
Common GO terms GO:0001664 - G protein-coupled receptor binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007213 - G protein-coupled acetylcholine receptor signaling pathway
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 689
Hs

1 359
+ Hs
+ Rn
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024