HitPredict

Interactor 1: KCNC1 (P25122)
Potassium voltage-gated channel subfamily C member 1 (NGK2) (RAW2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4)
Gene: KCNC1

Interactor 2: DLG1 (Q62696)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97)
Gene: DLG1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19213956
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019894 - kinesin binding GO:0030425 - dendrite GO:0042734 - presynaptic membrane GO:0043025 - neuronal cell body GO:0044325 - transmembrane transporter binding and 1 others more... GO:0045211 - postsynaptic membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 585 Rn			1 911
+	Hs
		819567 KCNC1_HUMAN (1-505): 4.82e-158: 463: 99.21		DLG1_HUMAN (1-911): 0: 705: 92.22
+	Hs
		602905 KCNA3_HUMAN (5-527): 6.87e-117: 360: 31.66		DLG1_HUMAN (1-911): 0: 705: 92.22
+	Hs
		608224 KCNA4_HUMAN (4-527): 9.52e-116: 359: 31.92		DLG1_HUMAN (1-911): 0: 705: 92.22
+	Hs
		608244 KCNA4_HUMAN (4-527): 9.52e-116: 359: 31.92		DLG3_HUMAN (107-911): 0: 586: 62.56
+	Hs
		1050021 KCNB2_HUMAN (5-571): 9.36e-135: 416: 29.13		SCRIB_HUMAN (217-395): 5.26e-23: 108: 41.18
+	Hs
		942389 KCND2_HUMAN (3-582): 8.29e-128: 390: 29.21		DLG4_HUMAN (157-406): 3.82e-24: 111: 22.71
+	Mm
		927733 KCNA2_MOUSE (2-527): 2.47e-120: 366: 32.40		DLG4_MOUSE (157-406): 3.36e-24: 111: 22.71
+	Hs
		558713 KCNA2_HUMAN (2-527): 8.35e-120: 365: 32.40		DLG4_HUMAN (157-406): 3.82e-24: 111: 22.71
+	Hs
		942333 KCNA1_HUMAN (3-527): 3.88e-119: 363: 32.58		DLG4_HUMAN (157-406): 3.82e-24: 111: 22.71
+	Hs
		159156 KCNA4_HUMAN (4-527): 9.52e-116: 359: 31.92		CSKP_HUMAN (12-429): 5.61e-25: 114: 12.10
+	Mm
		558703 KCNA1_MOUSE (3-527): 2.84e-118: 361: 32.20		DLG4_MOUSE (157-406): 3.36e-24: 111: 22.71
+	Hs
		602901 KCNA3_HUMAN (5-527): 6.87e-117: 360: 31.66		DLG4_HUMAN (157-406): 3.82e-24: 111: 22.71
+	Hs
		608221 KCNA4_HUMAN (4-527): 9.52e-116: 359: 31.92		DLG4_HUMAN (157-406): 3.82e-24: 111: 22.71
+	Mm
		558878 KCNA3_MOUSE (5-527): 1.25e-116: 358: 31.66		DLG4_MOUSE (157-406): 3.36e-24: 111: 22.71
+	Rn
		548174 KCNA4_RAT (4-527): 1.34e-114: 357: 31.73		DLG4_RAT (157-366): 6.44e-24: 110: 24.17
+	Hs
		608230 KCNA4_HUMAN (4-527): 9.52e-116: 359: 31.92		SCRIB_HUMAN (217-395): 5.26e-23: 108: 41.18
+	Hs
		608231 KCNA4_HUMAN (4-527): 9.52e-116: 359: 31.92		DLG2_HUMAN (376-769): 9.42e-23: 106: 19.75
+	Mm
		558896 KCNA3_MOUSE (5-527): 1.25e-116: 358: 31.66		SCRIB_MOUSE (227-541): 2.06e-18: 93.2: 26.50
+	Hs
		608222 KCNA4_HUMAN (4-527): 9.52e-116: 359: 31.92		EM55_HUMAN (158-389): 6.03e-18: 89.8: 15.92
+	Hs
		608232 KCNA4_HUMAN (4-527): 9.52e-116: 359: 31.92		MPP7_HUMAN (203-368): 3.41e-14: 78.7: 17.68