HitPredict

Interactor 1: MCM3 (P25205)
DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102)
Gene: MCM3

Interactor 2: FOXC1 (Q12948)
Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead-related transcription factor 3) (FREAC-3)
Gene: FOXC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34551306
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 808 Hs			1 553
+	Hs
		627224 MCM3_HUMAN (1-808): 0: 944: 100.00		FOXA1_HUMAN (14-357): 6.54e-35: 139: 30.52
+	Hs
		832412 MCM2_HUMAN (10-721): 0: 707: 30.62		FOXC1_HUMAN (1-553): 8.84e-82: 267: 100.00
+	Hs
		1021107 MCM6_HUMAN (2-800): 0: 688: 26.50		FOXC1_HUMAN (1-553): 8.84e-82: 267: 100.00
+	Hs
		708622 MCM5_HUMAN (9-713): 0: 685: 28.92		FOXC1_HUMAN (1-553): 8.84e-82: 267: 100.00
+	Hs
		708883 MCM7_HUMAN (10-669): 0: 650: 31.62		FOXC1_HUMAN (1-553): 8.84e-82: 267: 100.00
+	Hs
		708407 MCM4_HUMAN (9-739): 0: 661: 28.03		FOXA3_HUMAN (7-279): 3.13e-35: 137: 34.80
+	Hs
		708851 MCM7_HUMAN (10-669): 0: 650: 31.62		FOXA1_HUMAN (14-357): 6.54e-35: 139: 30.52