Interactor 1: MCM3 (P25205)
DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102)
Gene: MCM3
Interactor 2: MCM6 (Q14566)
DNA replication licensing factor MCM6 (EC 3.6.4.12) (p105MCM)
Gene: MCM6
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.967 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 27621311, 30108253, 33961781, 26496610, 17296731, 15232106 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification, protein array |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | MCM~MCM, MCM~MCM6_C, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM6_C~MCM_lid, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB |
| Common GO terms | GO:0000727 - double-strand break repair via break-induced replication GO:0000781 - chromosome, telomeric region GO:0003697 - single-stranded DNA binding GO:0005524 - ATP binding GO:0005634 - nucleus and 7 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
