HitPredict

Interactor 1: RAB3 (P25228)
Ras-related protein Rab-3
Gene: RAB3

Interactor 2: Q9VLB7 (Q9VLB7)
Rab GDP dissociation inhibitor
Gene: Gdi

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0007269 - neurotransmitter secretion GO:0008021 - synaptic vesicle GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 220 Dm			1 443
+	Hs
		591514 RAB3B_HUMAN (1-220): 2.86e-103: 298: 76.47		GDIA_HUMAN (1-440): 0: 678: 67.80
+	Hs
		678381 RAB8B_HUMAN (14-219): 6.61e-97: 282: 45.89		GDIA_HUMAN (1-440): 0: 678: 67.80
+	Hs
		838673 RAB8B_HUMAN (14-219): 6.61e-97: 282: 45.89		GDIB_HUMAN (1-440): 0: 670: 67.80
+	Mm
		838710 RAB3A_MOUSE (1-220): 1.83e-91: 269: 76.92		GDIA_MOUSE (1-440): 0: 680: 68.03
+	Hs
		591453 RAB3A_HUMAN (1-220): 2.71e-91: 268: 76.47		GDIA_HUMAN (1-440): 0: 678: 67.80
+	Hs
		678336 RAB8A_HUMAN (14-215): 1.96e-90: 266: 48.52		GDIA_HUMAN (1-440): 0: 678: 67.80
+	Mm
		838709 RAB1A_MOUSE (12-219): 5.8e-89: 262: 41.83		GDIA_MOUSE (1-440): 0: 680: 68.03
+	Hs
		678344 RAB1A_HUMAN (12-219): 5.8e-89: 262: 41.83		GDIA_HUMAN (1-440): 0: 678: 67.80
+	Hs
		591462 RAB3A_HUMAN (1-220): 2.71e-91: 268: 76.47		GDIB_HUMAN (1-440): 0: 670: 67.80
+	Hs
		838616 RAB8A_HUMAN (14-215): 1.96e-90: 266: 48.52		GDIB_HUMAN (1-440): 0: 670: 67.80
+	Hs
		838625 RAB1A_HUMAN (12-219): 5.8e-89: 262: 41.83		GDIB_HUMAN (1-440): 0: 670: 67.80
+	Hs
		591507 RAB3B_HUMAN (1-220): 2.86e-103: 298: 76.47		RAE2_HUMAN (4-67): 2.76e-13: 73.9: 39.06
+	Hs
		642738 RAB8B_HUMAN (14-219): 6.61e-97: 282: 45.89		RAE2_HUMAN (4-67): 2.76e-13: 73.9: 39.06
+	Hs
		622608 RAB8B_HUMAN (14-219): 6.61e-97: 282: 45.89		RAE1_HUMAN (4-47): 1.12e-12: 71.9: 52.27
+	Hs
		591451 RAB3A_HUMAN (1-220): 2.71e-91: 268: 76.47		RAE2_HUMAN (4-67): 2.76e-13: 73.9: 39.06
+	Hs
		591450 RAB3A_HUMAN (1-220): 2.71e-91: 268: 76.47		RAE1_HUMAN (4-47): 1.12e-12: 71.9: 52.27
+	Hs
		642718 RAB8A_HUMAN (14-215): 1.96e-90: 266: 48.52		RAE2_HUMAN (4-67): 2.76e-13: 73.9: 39.06
+	Hs
		622570 RAB8A_HUMAN (14-215): 1.96e-90: 266: 48.52		RAE1_HUMAN (4-47): 1.12e-12: 71.9: 52.27
+	Hs
		642723 RAB1A_HUMAN (12-219): 5.8e-89: 262: 41.83		RAE2_HUMAN (4-67): 2.76e-13: 73.9: 39.06
+	Hs
		622577 RAB1A_HUMAN (12-219): 5.8e-89: 262: 41.83		RAE1_HUMAN (4-47): 1.12e-12: 71.9: 52.27