HitPredict

Interactor 1: SIS1 (P25294)
Protein SIS1
Gene: SIS1

Interactor 2: MCR1 (P36060)
NADH-cytochrome b5 reductase 2 (EC 1.6.2.2) (Mitochondrial cytochrome b reductase) (p34/p32) [Cleaved into: NADH-cytochrome b5 reductase p34 form; NADH-cytochrome b5 reductase p32 form]
Gene: MCR1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.50	0.570

Property	Details
Experiments	35876647, 37845327
Identification Methods	pull down, affinity chromatography technology, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 352 Sc			1 302
+	Sc
		633130 MAS5_YEAST (1-352): 1.41e-111: 332: 28.13		MCR1_YEAST (1-302): 9.84e-103: 304: 100.00
+	Hs
		681343 DNJA1_HUMAN (1-352): 2.53e-121: 357: 28.93		NOS2_HUMAN (17-300): 1.26e-69: 235: 13.10
+	Hs
		243314 DNJA2_HUMAN (2-352): 5.07e-121: 356: 28.09		NOS2_HUMAN (17-300): 1.26e-69: 235: 13.10
+	Sc
		633192 MAS5_YEAST (1-352): 1.41e-111: 332: 28.13		NCB5R_YEAST (37-302): 7.16e-79: 243: 30.37
+	Sc
		627995 SIS1_YEAST (1-352): 6.96e-105: 313: 100.00		NCB5R_YEAST (37-302): 7.16e-79: 243: 30.37
+	Sc
		628628 SIS1_YEAST (1-352): 6.96e-105: 313: 100.00		PGA3_YEAST (28-302): 4.69e-77: 239: 31.64
+	Sc
		628071 SIS1_YEAST (1-352): 6.96e-105: 313: 100.00		FHP_YEAST (48-300): 1.43e-46: 162: 16.54