Protein: ERCC5
DNA excision repair protein ERCC-5 (EC 3.1.-.-) (DNA repair protein complementing XP-G cells) (XPG) (Xeroderma pigmentosum group G-complementing protein)

Gene: ERCC5
Organism: Homo sapiens
Interactions: 50
UniProt ID: P28715

Gene Ontology (top 5):
GO:0000109 - nucleotide-excision repair complex
GO:0000405 - bubble DNA binding
GO:0000724 - double-strand break repair via homologous recombination
GO:0000993 - RNA polymerase II complex binding
GO:0003684 - damaged DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

659911

CDK7
Cyclin-dependent kinase 7

8

6

High-throughput

0.751

High

517072

PCNA
Proliferating cell nuclear antigen

1

6

Small-scale

0.747

High

584550

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

4

1

Small-scale

0.697

High

659903

TF2H1
General transcription factor IIH subunit 1

4

1

Small-scale

0.689

High

659913

CCNH
Cyclin-H

3

7

High-throughput

0.667

High

659920

ERCC6
DNA excision repair protein ERCC-6

3

1

Small-scale

0.646

High

574127

ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD

2

3

Small-scale

0.639

High

624778

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

1

Small-scale

0.624

High

659926

TF2H2
General transcription factor IIH subunit 2

2

1

Small-scale

0.611

High

659918

NTH
Endonuclease III-like protein 1

2

0

Small-scale

0.577

High

659904

BRCA1
Breast cancer type 1 susceptibility protein

1

1

Small-scale

0.561

High

659919

EWS
RNA-binding protein EWS

1

1

High-throughput

0.541

High

622925

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

0

Small-scale

0.537

High

659912

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.537

High

659921

RAD51
DNA repair protein RAD51 homolog 1

1

0

Small-scale

0.537

High

125848

CDC7
Cell division cycle 7-related protein kinase

1

5

High-throughput

0.536

High

586576

CSK22
Casein kinase II subunit alpha'

1

3

High-throughput

0.536

High

659906

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

1

High-throughput

0.536

High

659917

CSK21
Casein kinase II subunit alpha

1

4

High-throughput

0.536

High

388248

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.518

High

659905

BCL6
B-cell lymphoma 6 protein

1

0

Small-scale

0.513

High

659914

MAT1
CDK-activating kinase assembly factor MAT1

1

0

High-throughput

0.513

High

659927

TF2H3
General transcription factor IIH subunit 3

1

0

High-throughput

0.513

High

659929

TF2H5
General transcription factor IIH subunit 5

1

0

High-throughput

0.513

High

659936

TF2H4
General transcription factor IIH subunit 4

1

0

High-throughput

0.513

High

659938

TGS1
Trimethylguanosine synthase

1

0

High-throughput

0.513

High

652753

APEX1
DNA repair nuclease/redox regulator APEX1

1

1

High-throughput

0.479

High

659907

CENPA
Histone H3-like centromeric protein A

1

4

High-throughput

0.479

High

659908

CLK1
Dual specificity protein kinase CLK1

1

11

High-throughput

0.479

High

659909

CLK2
Dual specificity protein kinase CLK2

1

11

High-throughput

0.479

High

659910

CLK3
Dual specificity protein kinase CLK3

1

11

High-throughput

0.479

High

659915

H2B1C
Histone H2B type 1-C/E/F/G/I

1

3

High-throughput

0.479

High

659923

RFA4
Replication protein A 30 kDa subunit

1

3

High-throughput

0.479

High

659924

SQSTM
Sequestosome-1

1

1

Small-scale

0.479

High

659925

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

4

High-throughput

0.479

High

659928

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

659931

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

659934

NUP43
Nucleoporin Nup43

1

1

High-throughput

0.479

High

659939

MEP50
Methylosome protein WDR77

1

1

High-throughput

0.479

High

659942

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

659922

TAF10
Transcription initiation factor TFIID subunit 10

1

0

High-throughput

0.458

High

659930

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.458

High

659932

PALB2
Partner and localizer of BRCA2

1

0

Small-scale

0.458

High

659935

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

659940

PIDD1
p53-induced death domain-containing protein 1

1

0

Small-scale

0.458

High

659941

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

360620

SPTA1
Spectrin alpha chain, erythrocytic 1

1

1

Small-scale

0.437

High

659916

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.437

High

659933

DHX40
Probable ATP-dependent RNA helicase DHX40

1

0

High-throughput

0.249

Low

659937

SNX27
Sorting nexin-27

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024