Interactor 1: PGTB2 (P20133)
Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Type II protein geranyl-geranyltransferase subunit beta) (PGGT) (YPT1/SEC4 proteins geranylgeranyltransferase subunit beta)
Gene: BET2

Interactor 2: RAEP (P32864)
Rab proteins geranylgeranyltransferase component A (Rab escort protein) (REP)
Gene: MRS6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.694

The method score is based on:

Property Details
Experiments 12022885, 8183917, 18719252, 40049413
Identification Methods fluorescent resonance energy transfer, pull down, enzymatic study, two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005968 - Rab-protein geranylgeranyltransferase complex
GO:0006612 - protein targeting to membrane
GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0031267 - small GTPase binding
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 325
Sc

1 603
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025