HitPredict

Interactor 1: RV161 (P25343)
Reduced viability upon starvation protein 161
Gene: RVS161

Interactor 2: RSP5 (P39940)
E3 ubiquitin-protein ligase RSP5 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase RSP5) (Reverses SPT-phenotype protein 5)
Gene: RSP5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.600

Property	Details
Experiments	26508657, 18719252
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030479 - actin cortical patch
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 265 Sc			1 809
+	Sc
		764057 RV167_YEAST (1-260): 7.78e-70: 224: 25.27		RSP5_YEAST (1-809): 0: 825: 100.00
+	Hs
		131270 BIN1_HUMAN (3-230): 3.22e-65: 215: 19.16		ITCH_HUMAN (1-809): 0: 727: 34.62
+	Mm
		139040 BIN1_MOUSE (3-230): 7.65e-63: 208: 19.16		HUWE1_MOUSE (352-808): 7.81e-167: 538: 37.42
+	Dm
		1180693 Q7KLE5_DROME (1-236): 4.2e-65: 215: 21.25		NEDD4_DROME (4-400): 2.42e-26: 117: 18.61
+	Hs
		1350514 3BP1_HUMAN (6-233): 8.37e-09: 57.9: 11.28		HECW2_HUMAN (10-413): 1.88e-09: 63.7: 12.12