Interactor 1: TNR6 (P25445)
Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95)
Gene: FAS

Interactor 2: DAXX (Q9UER7)
Death domain-associated protein 6 (Daxx) (hDaxx) (ETS1-associated protein 1) (EAP1) (Fas death domain-associated protein)
Gene: DAXX

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.749

The method score is based on:

Property Details
Experiments 9990010, 20565132, 14637155, 11495919, 11773067, 9215629, 11003656
Identification Methods pull down, affinity chromatography technology, two hybrid, coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0005829 - cytosol
GO:0016604 - nuclear body
GO:0042981 - regulation of apoptotic process
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 335
Hs

1 740
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024