HitPredict

Interactor 1: MPRD (P20645)
Cation-dependent mannose-6-phosphate receptor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46)
Gene: M6PR

Interactor 2: GGA3 (Q9NZ52)
ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3)
Gene: GGA3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	11387475, 11859375
Identification Methods	two hybrid, x-ray crystallography
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005802 - trans-Golgi network GO:0006622 - protein targeting to lysosome GO:0140318 - protein transporter activity
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 277 Hs			1 723
+	Hs
		633875 MPRD_HUMAN (1-277): 0: 536: 100.00		GGA1_HUMAN (2-723): 1.1e-91: 301: 39.78
+	Hs
		633874 MPRD_HUMAN (1-277): 0: 536: 100.00		GGA2_HUMAN (456-721): 1.1e-25: 114: 34.83