HitPredict

Interactor 1: DCC1 (P25559)
Sister chromatid cohesion protein DCC1 (Defective in sister chromatid cohesion protein 1)
Gene: DCC1

Interactor 2: RFC5 (P38251)
Replication factor C subunit 5 (Replication factor C5) (Activator 1 40 kDa subunit)
Gene: RFC5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	16554755, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007064 - mitotic sister chromatid cohesion GO:0031390 - Ctf18 RFC-like complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 380 Sc			1 354
+	Sc
		634057 DCC1_YEAST (1-380): 0: 514: 100.00		RFC2_YEAST (2-351): 3.23e-97: 293: 25.63
+	Sc
		634048 DCC1_YEAST (1-380): 0: 514: 100.00		RFC3_YEAST (3-354): 1.08e-86: 266: 22.25
+	Sc
		634056 DCC1_YEAST (1-380): 0: 514: 100.00		RFC4_YEAST (3-349): 8.42e-84: 258: 22.19
+	Hs
		722030 DCC1_HUMAN (17-380): 3.81e-127: 373: 23.00		RFC4_HUMAN (2-353): 5.88e-103: 309: 29.26
+	Hs
		778028 DCC1_HUMAN (17-380): 3.81e-127: 373: 23.00		RFC3_HUMAN (1-351): 1.57e-101: 305: 43.88
+	Hs
		722148 DCC1_HUMAN (17-380): 3.81e-127: 373: 23.00		RFC2_HUMAN (3-352): 1.34e-92: 282: 24.29
+	Hs
		777916 DCC1_HUMAN (17-380): 3.81e-127: 373: 23.00		RFC5_HUMAN (3-354): 7.94e-90: 274: 23.51