Protein: VMAT2
Synaptic vesicular amine transporter (Solute carrier family 18 member 2) (Vesicular amine transporter 2) (VAT2) (Vesicular monoamine transporter 2)

Gene: VMAT2, SLC18A2
Organism: Homo sapiens
Interactions: 162
UniProt ID: Q05940

Gene Ontology (top 5):
GO:0001975 - response to amphetamine
GO:0002552 - serotonin secretion by mast cell
GO:0002553 - histamine secretion by mast cell
GO:0005335 - serotonin:sodium:chloride symporter activity
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1053033

MFSD8
Major facilitator superfamily domain-containing protein 8

1

9

High-throughput

0.618

High

668213

CXCR2
C-X-C chemokine receptor type 2

2

3

High-throughput

0.606

High

722443

CTR1
High affinity cationic amino acid transporter 1

2

5

High-throughput

0.606

High

1053017

BRID5
BRICHOS domain-containing protein 5

2

1

High-throughput

0.606

High

1053037

GP151
G-protein coupled receptor 151

2

1

High-throughput

0.606

High

1052987

MTX1
Metaxin-1

2

2

High-throughput

0.601

High

1052988

RAB32
Ras-related protein Rab-32

2

4

High-throughput

0.601

High

1053010

SCMC1
Mitochondrial adenyl nucleotide antiporter SLC25A24

2

1

High-throughput

0.601

High

1052995

NKG7
Protein NKG7

2

0

High-throughput

0.580

High

1053009

MFSD5
Molybdate-anion transporter

2

0

High-throughput

0.580

High

1053049

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

2

0

High-throughput

0.580

High

641162

FGFR2
Fibroblast growth factor receptor 2

1

5

High-throughput

0.575

High

942486

DHB7
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

2

2

High-throughput

0.549

High

1052997

CL16A
Protein CLEC16A

2

1

High-throughput

0.549

High

1013198

ATL3
ADAMTS-like protein 3

1

0

High-throughput

0.546

High

1053054

PARK7
Parkinson disease protein 7

1

0

Small-scale

0.537

High

226424

SNG2
Synaptogyrin-2

1

2

High-throughput

0.536

High

228077

PM34
Peroxisomal membrane protein PMP34

1

3

High-throughput

0.536

High

333571

NDUC2
NADH dehydrogenase [ubiquinone] 1 subunit C2

1

1

High-throughput

0.536

High

403160

APOB
Apolipoprotein B-100

1

1

High-throughput

0.536

High

658695

JAK1
Tyrosine-protein kinase JAK1

1

6

High-throughput

0.536

High

755548

TTK
Dual specificity protein kinase TTK

1

2

High-throughput

0.536

High

1015005

ARF5
ADP-ribosylation factor 5

1

3

High-throughput

0.536

High

1052993

NOMO1
BOS complex subunit NOMO1

1

2

High-throughput

0.536

High

1053004

AB17B
Alpha/beta hydrolase domain-containing protein 17B

1

3

High-throughput

0.536

High

1053005

ECM29
Proteasome adapter and scaffold protein ECM29

1

1

High-throughput

0.536

High

1053015

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

2

High-throughput

0.536

High

1053029

ORML3
ORM1-like protein 3

1

2

High-throughput

0.536

High

1053035

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

2

High-throughput

0.536

High

1053038

NEK7
Serine/threonine-protein kinase Nek7

1

2

High-throughput

0.536

High

1053042

YLAT2
Y+L amino acid transporter 2

1

7

High-throughput

0.536

High

1053048

RB39B
Ras-related protein Rab-39B

1

3

High-throughput

0.536

High

1053055

S29A1
Equilibrative nucleoside transporter 1

1

1

High-throughput

0.536

High

1053057

GCP2
Gamma-tubulin complex component 2

1

1

High-throughput

0.536

High

1053073

PXMP2
Peroxisomal membrane protein 2

1

3

High-throughput

0.536

High

1053080

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

1

1

High-throughput

0.536

High

1053081

GCP4
Gamma-tubulin complex component 4

1

1

High-throughput

0.536

High

1053092

PEX16
Peroxisomal membrane protein PEX16

1

1

High-throughput

0.536

High

173695

BTAF1
TATA-binding protein-associated factor 172

1

0

High-throughput

0.513

High

252856

EXOC3
Exocyst complex component 3

1

0

High-throughput

0.513

High

271699

HIP1R
Huntingtin-interacting protein 1-related protein

1

0

High-throughput

0.513

High

319697

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.513

High

630417

RAB3A
Ras-related protein Rab-3A

1

0

High-throughput

0.513

High

897564

KNTC1
Kinetochore-associated protein 1

1

0

High-throughput

0.513

High

1052996

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.513

High

1053007

ATLA3
Atlastin-3

1

0

High-throughput

0.513

High

1053014

MZT2B
Mitotic-spindle organizing protein 2B

1

0

High-throughput

0.513

High

1053016

INT5
Integrator complex subunit 5

1

0

High-throughput

0.513

High

1053023

DYM
Dymeclin

1

0

High-throughput

0.513

High

1053030

VPS52
Vacuolar protein sorting-associated protein 52 homolog

1

0

High-throughput

0.513

High

1053034

EXOC6
Exocyst complex component 6

1

0

High-throughput

0.513

High

1053050

VPS50
Syndetin

1

0

High-throughput

0.513

High

1053051

EXOC2
Exocyst complex component 2

1

0

High-throughput

0.513

High

1053052

TLCD4
TLC domain-containing protein 4

1

0

High-throughput

0.513

High

1053059

NFIP1
NEDD4 family-interacting protein 1

1

0

High-throughput

0.513

High

1053072

CD320
CD320 antigen

1

0

High-throughput

0.513

High

1053074

SERC1
Serine incorporator 1

1

0

High-throughput

0.513

High

1053075

MITOS
Mitochondrial potassium channel ATP-binding subunit

1

0

High-throughput

0.513

High

1053078

STML1
Stomatin-like protein 1

1

0

High-throughput

0.513

High

1053086

DD19B
ATP-dependent RNA helicase DDX19B

1

0

High-throughput

0.513

High

1053088

BAIP2
BAR/IMD domain-containing adapter protein 2

1

0

High-throughput

0.513

High

1053090

TELO2
Telomere length regulation protein TEL2 homolog

1

0

High-throughput

0.513

High

1053068

DNJC5
DnaJ homolog subfamily C member 5

1

4

High-throughput

0.501

High

122611

UBXN8
UBX domain-containing protein 8

1

1

High-throughput

0.489

High

230896

ORC5
Origin recognition complex subunit 5

1

5

High-throughput

0.489

High

665087

COT2
COUP transcription factor 2

1

2

High-throughput

0.489

High

847392

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

1

2

High-throughput

0.489

High

1052363

RN5A
2-5A-dependent ribonuclease

1

1

High-throughput

0.489

High

1052998

S2552
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A52

1

3

High-throughput

0.489

High

1053000

ORML2
ORM1-like protein 2

1

2

High-throughput

0.489

High

1053001

MTX3
Metaxin-3

1

2

High-throughput

0.489

High

1053003

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

1

High-throughput

0.489

High

1053008

SCMC2
Mitochondrial adenyl nucleotide antiporter SLC25A25

1

2

High-throughput

0.489

High

1053021

HACD2
Very-long-chain

1

2

High-throughput

0.489

High

1053024

ADCK1
AarF domain-containing protein kinase 1

1

4

High-throughput

0.489

High

1053040

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

2

High-throughput

0.489

High

1053047

OTUL
Ubiquitin thioesterase otulin

1

2

High-throughput

0.489

High

1053058

S2533
Solute carrier family 25 member 33

1

3

High-throughput

0.489

High

1053061

FUND2
FUN14 domain-containing protein 2

1

3

High-throughput

0.489

High

1053065

ELOV4
Very long chain fatty acid elongase 4

1

4

High-throughput

0.489

High

1053071

NEK6
Serine/threonine-protein kinase Nek6

1

2

High-throughput

0.489

High

1033921

SC6A3
Sodium-dependent dopamine transporter

1

1

Small-scale

0.479

High

515695

TPC2B
Trafficking protein particle complex subunit 2B

1

0

High-throughput

0.458

High

127316

LEG8
Galectin-8

1

6

High-throughput

0.445

High

211918

SPIT1
Kunitz-type protease inhibitor 1

1

8

High-throughput

0.445

High

350362

ABHGA
Phosphatidylserine lipase ABHD16A

1

2

High-throughput

0.445

High

609655

LEG3
Galectin-3

1

6

High-throughput

0.445

High

655166

SFPQ
Splicing factor, proline- and glutamine-rich

1

1

High-throughput

0.445

High

844193

ECE1
Endothelin-converting enzyme 1

1

4

High-throughput

0.445

High

876674

HSP13
Heat shock 70 kDa protein 13

1

4

High-throughput

0.445

High

901201

RAB7A
Ras-related protein Rab-7a

1

1

High-throughput

0.445

High

957916

RAB14
Ras-related protein Rab-14

1

2

High-throughput

0.445

High

982069

RAP1A
Ras-related protein Rap-1A

1

1

High-throughput

0.445

High

1043118

TAP1
Antigen peptide transporter 1

1

1

High-throughput

0.445

High

1052985

VAC14
Protein VAC14 homolog

1

2

High-throughput

0.445

High

1052986

MTM1
Myotubularin

1

2

High-throughput

0.445

High

1052989

ERG1
Squalene monooxygenase

1

3

High-throughput

0.445

High

1052991

ACOX1
Peroxisomal acyl-coenzyme A oxidase 1

1

5

High-throughput

0.445

High

1052999

ANO6
Anoctamin-6

1

1

High-throughput

0.445

High

1053011

RETST
All-trans-retinol 13,14-reductase

1

3

High-throughput

0.445

High

1053018

ATRAP
Type-1 angiotensin II receptor-associated protein

1

1

High-throughput

0.445

High

1053019

LCLT1
Lysocardiolipin acyltransferase 1

1

2

High-throughput

0.445

High

1053022

TMTC3
Protein O-mannosyl-transferase TMTC3

1

1

High-throughput

0.445

High

1053028

WDFY1
WD repeat and FYVE domain-containing protein 1

1

1

High-throughput

0.445

High

1053043

TBCD5
TBC1 domain family member 5

1

1

High-throughput

0.445

High

1053064

MTMRC
Myotubularin-related protein 12

1

2

High-throughput

0.445

High

1053076

ANO10
Anoctamin-10

1

1

High-throughput

0.445

High

1053077

MTMRA
Myotubularin-related protein 10

1

2

High-throughput

0.445

High

1053082

SEC63
Translocation protein SEC63 homolog

1

2

High-throughput

0.445

High

1053089

FND3A
Fibronectin type-III domain-containing protein 3A

1

2

High-throughput

0.445

High

1053093

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

2

High-throughput

0.445

High

166904

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.426

High

216335

MBTP2
Membrane-bound transcription factor site-2 protease

1

0

High-throughput

0.426

High

249973

OGA
Protein O-GlcNAcase

1

0

High-throughput

0.426

High

387411

APOE
Apolipoprotein E

1

0

High-throughput

0.426

High

591609

H2AX
Histone H2AX

1

0

High-throughput

0.426

High

789889

FDFT
Squalene synthase

1

0

High-throughput

0.426

High

827754

STAT3
Signal transducer and activator of transcription 3

1

0

High-throughput

0.426

High

900784

RAB5C
Ras-related protein Rab-5C

1

0

High-throughput

0.426

High

1052994

VAS1
V-type proton ATPase subunit S1

1

0

High-throughput

0.426

High

1053006

ZDH20
Palmitoyltransferase ZDHHC20

1

0

High-throughput

0.426

High

1053041

DCAKD
Dephospho-CoA kinase domain-containing protein

1

0

High-throughput

0.426

High

1053053

SEC62
Translocation protein SEC62

1

0

High-throughput

0.426

High

1053066

EHD4
EH domain-containing protein 4

1

0

High-throughput

0.426

High

1053091

SNX8
Sorting nexin-8

1

0

High-throughput

0.426

High

231470

ORC4
Origin recognition complex subunit 4

1

5

High-throughput

0.407

High

611089

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

1

High-throughput

0.407

High

853096

ACDSB
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial

1

2

High-throughput

0.407

High

903555

IDH3G
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial

1

1

High-throughput

0.407

High

1053031

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.407

High

1053056

MGME1
Mitochondrial genome maintenance exonuclease 1

1

1

High-throughput

0.407

High

1053067

S2532
Solute carrier family 25 member 32

1

4

High-throughput

0.407

High

1053084

XPO7
Exportin-7

1

2

High-throughput

0.407

High

1053085

RAB21
Ras-related protein Rab-21

1

4

High-throughput

0.407

High

1053094

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

2

High-throughput

0.407

High

1053046

TOM6
Mitochondrial import receptor subunit TOM6 homolog

2

0

High-throughput

0.316

High

1053060

TM109
Voltage-gated monoatomic cation channel TMEM109

2

0

High-throughput

0.316

High

1053062

FHR5
Complement factor H-related protein 5

2

0

High-throughput

0.316

High

1053025

DAAF5
Dynein axonemal assembly factor 5

2

0

High-throughput

0.313

High

1053044

FAKD4
FAST kinase domain-containing protein 4

2

0

High-throughput

0.313

High

1053079

MTFP1
Mitochondrial fission process protein 1

2

0

High-throughput

0.313

High

129863

GET1
Guided entry of tail-anchored proteins factor 1

1

0

High-throughput

0.279

Low

137219

EXOC5
Exocyst complex component 5

1

0

High-throughput

0.279

Low

339261

MPC2
Mitochondrial pyruvate carrier 2

1

0

High-throughput

0.279

Low

1052990

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

High-throughput

0.279

Low

1052992

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

1

0

High-throughput

0.279

Low

1053002

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

0

High-throughput

0.279

Low

1053013

TTI2
TELO2-interacting protein 2

1

0

High-throughput

0.279

Low

1053020

MIC27
MICOS complex subunit MIC27

1

0

High-throughput

0.279

Low

1053026

TPPC5
Trafficking protein particle complex subunit 5

1

0

High-throughput

0.279

Low

1053027

T126B
Complex I assembly factor TMEM126B, mitochondrial

1

0

High-throughput

0.279

Low

1053032

MCU
Calcium uniporter protein, mitochondrial

1

0

High-throughput

0.279

Low

1053039

COG1
Conserved oligomeric Golgi complex subunit 1

1

0

High-throughput

0.279

Low

1053069

TFB2M
Dimethyladenosine transferase 2, mitochondrial

1

0

High-throughput

0.279

Low

1053087

DOLK
Dolichol kinase

1

0

High-throughput

0.279

Low

219299

B4GA1
Beta-1,4-glucuronyltransferase 1

1

0

High-throughput

0.232

Low

1053012

TM214
Transmembrane protein 214

1

0

High-throughput

0.232

Low

1053036

RDH11
Retinol dehydrogenase 11

1

0

High-throughput

0.232

Low

1053045

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

1

0

High-throughput

0.232

Low

1053063

UCK2
Uridine-cytidine kinase 2

1

0

High-throughput

0.232

Low

1053070

ARMT1
Damage-control phosphatase ARMT1

1

0

High-throughput

0.232

Low

1053083

PCYOX
Prenylcysteine oxidase 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025