Interactor 1: SPB1 (P25582)
27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase (EC 2.1.1.167) (2'-O-ribose RNA methyltransferase SPB1) (AdoMet-dependent rRNA methyltransferase SPB1) (S-adenosyl-L-methionine-dependent methyltransferase) (Suppressor of PAB1 protein 1)
Gene: SPB1

Interactor 2: ERB1 (Q04660)
Ribosome biogenesis protein ERB1 (Eukaryotic ribosome biogenesis protein 1)
Gene: ERB1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 36929751, 37968396
Identification Methods x-ray crystallography, affinity chromatography technology
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FtsJ~WD40
Common GO terms GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0030687 - preribosome, large subunit precursor
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 841
Sc

1 807
+ Dm
+ Sc
+ Sc
+ Hs
+ Hs
+ Sc
+ Sp
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024