HitPredict

Interactor 1: SYP1 (P25623)
Suppressor of yeast profilin deletion
Gene: SYP1

Interactor 2: CENPA (P36012)
Histone H3-like centromeric protein CSE4 (CENP-A homolog) (CENPA homolog) (Chromosome segregation protein 4)
Gene: CSE4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	21070971
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 870 Sc			1 229
+	Sc
		730797 SEC31_YEAST (208-648): 2.9e-09: 63.2: 11.60		CENPA_YEAST (1-229): 4.31e-86: 256: 100.00
+	Hs
		934668 ANK2_HUMAN (260-774): 1.68e-11: 70.5: 11.77		H31_HUMAN (93-227): 9.76e-53: 168: 51.10
+	Hs
		934908 SRCAP_HUMAN (81-652): 1.99e-11: 70.5: 14.03		H31_HUMAN (93-227): 9.76e-53: 168: 51.10
+	Hs
		952426 SRCAP_HUMAN (81-652): 1.99e-11: 70.5: 14.03		H33_HUMAN (93-227): 3.02e-51: 164: 51.83
+	Hs
		965127 ANK2_HUMAN (260-774): 1.68e-11: 70.5: 11.77		H32_HUMAN (93-227): 3.71e-51: 164: 51.83
+	Hs
		934763 MDC1_HUMAN (41-652): 1.54e-09: 64: 12.86		H31_HUMAN (93-227): 9.76e-53: 168: 51.10
+	Hs
		624861 RPB1_HUMAN (383-508): 3.99e-09: 62.8: 20.64		H31_HUMAN (93-227): 9.76e-53: 168: 51.10
+	Hs
		935004 KMT2C_HUMAN (311-654): 5.01e-09: 62.4: 16.19		H31_HUMAN (93-227): 9.76e-53: 168: 51.10
+	Hs
		952338 MDC1_HUMAN (41-652): 1.54e-09: 64: 12.86		H33_HUMAN (93-227): 3.02e-51: 164: 51.83
+	Hs
		1086228 KMT2C_HUMAN (311-654): 5.01e-09: 62.4: 16.19		H31T_HUMAN (93-227): 1.42e-51: 165: 48.91
+	Hs
		1174600 KMT2C_HUMAN (311-654): 5.01e-09: 62.4: 16.19		H32_HUMAN (93-227): 3.71e-51: 164: 51.83
+	Hs
		952479 KMT2C_HUMAN (311-654): 5.01e-09: 62.4: 16.19		H33_HUMAN (93-227): 3.02e-51: 164: 51.83
+	Hs
		1174677 RERE_HUMAN (182-621): 6.12e-09: 62.1: 13.79		H32_HUMAN (93-227): 3.71e-51: 164: 51.83