HitPredict

Interactor 1: PWP2 (P25635)
Periodic tryptophan protein 2 (U three protein 1) (U3 small nucleolar RNA-associated protein 1) (U3 snoRNA-associated protein 1)
Gene: PWP2

Interactor 2: NOC4 (Q06512)
Nucleolar complex protein 4 (U three protein 19) (U3 small nucleolar RNA-associated protein 19) (U3 snoRNA-associated protein 19)
Gene: NOC4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 11805826, 12150911, 16554755, 16429126, 28244370, 29361028, 35385737, 32943521, 35650250, 37968396
Identification Methods tandem affinity purification, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000028 - ribosomal small subunit assembly
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005654 - nucleoplasm
and 4 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 923
Sc

1 552
+ Sc
+ Sc
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024