HitPredict

Interactor 1: PAT1 (P25644)
Deadenylation-dependent mRNA-decapping factor PAT1 (DNA topoisomerase 2-associated protein PAT1) (Decapping activator and translational repressor PAT1) (Topoisomerase II-associated protein PAT1) (mRNA turnover protein 1)
Gene: PAT1

Interactor 2: LSM8 (P47093)
U6 snRNA-associated Sm-like protein LSm8
Gene: LSM8

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.835

Property	Details
Experiments	9207794, 11283351, 10900456
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	LSM~PAT1
Common GO terms	GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 796 Sc			1 109
+	Sc
		635880 PAT1_YEAST (1-796): 0: 845: 100.00		LSM1_YEAST (2-108): 1.12e-29: 106: 20.18
+	Sc
		635902 PAT1_YEAST (1-796): 0: 845: 100.00		LSM7_YEAST (5-71): 3.29e-13: 62.3: 15.00
+	Sc
		635906 PAT1_YEAST (1-796): 0: 845: 100.00		LSM3_YEAST (5-76): 5.4e-10: 53.5: 22.22
+	Sp
		194958 PAT1_SCHPO (1-788): 1.49e-177: 530: 24.83		LSM1_SCHPO (2-102): 7.94e-28: 100: 24.55
+	Sp
		194951 PAT1_SCHPO (1-788): 1.49e-177: 530: 24.83		LSM7_SCHPO (5-81): 4.07e-21: 82.4: 17.44
+	Dm
		1364801 Q9VEN9_DROME (91-678): 2.21e-107: 353: 15.77		Q9W2K2_DROME (2-88): 2.47e-25: 93.9: 23.91
+	Dm
		1364795 Q9VEN9_DROME (91-678): 2.21e-107: 353: 15.77		Q9VJI7_DROME (5-80): 1.86e-15: 68.1: 18.39
+	Hs
		87373 PATL2_HUMAN (171-685): 2.35e-87: 288: 13.49		LSM1_HUMAN (2-102): 1.21e-28: 102: 21.70
+	Hs
		167703 PATL1_HUMAN (51-684): 1.74e-79: 273: 16.99		LSM1_HUMAN (2-102): 1.21e-28: 102: 21.70
+	Hs
		1198409 PATL1_HUMAN (51-684): 1.74e-79: 273: 16.99		LSM7_HUMAN (5-81): 4.87e-19: 77: 17.24