Interactor 1: SRB8 (P25648)
Mediator of RNA polymerase II transcription subunit 12 (Mediator complex subunit 12) (Suppressor of RNA polymerase B 8)
Gene: SRB8

Interactor 2: SSN8 (P47821)
RNA polymerase II holoenzyme cyclin-like subunit (Suppressor of RNA polymerase B 11)
Gene: SSN8

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.735

The method score is based on:

Property Details
Experiments 11805826, 33933450, 37968396, 12200444, 33523904, 16429126
Identification Methods tandem affinity purification, pull down, affinity chromatography technology
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000411 - positive regulation of transcription by galactose
GO:0016592 - mediator complex
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:1990508 - CKM complex
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 1427
Sc

1 323
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Sp
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024