Protein: ODO1
2-oxoglutarate dehydrogenase, mitochondrial (OGDH) (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (OGDHC subunit E1) (Alpha-ketoglutarate dehydrogenase complex subunit E1) (alpha-KGDHC subunit E1)

Gene: ODO1, KGD1
Organism: Saccharomyces cerevisiae S288C
Interactions: 109
UniProt ID: P20967

Gene Ontology (top 5):
GO:0004591 - oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0005739 - mitochondrion
GO:0006099 - tricarboxylic acid cycle
GO:0006103 - 2-oxoglutarate metabolic process
GO:0030976 - thiamine pyrophosphate binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

619325

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

8

14

Small-scale

0.969

High

484718

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

5

9

Small-scale

0.716

High

627070

KGD4
Alpha-ketoglutarate dehydrogenase subunit 4, mitochondrial

5

0

Small-scale

0.686

High

594877

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

12

High-throughput

0.618

High

635926

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

13

High-throughput

0.618

High

635944

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

11

High-throughput

0.618

High

510185

HSP77
Import motor subunit, mitochondrial

2

5

High-throughput

0.584

High

635953

MIC60
MICOS complex subunit MIC60

2

1

High-throughput

0.584

High

392216

HSP82
ATP-dependent molecular chaperone HSP82

2

2

High-throughput

0.555

High

635995

RU2A
U2 small nuclear ribonucleoprotein A'

2

1

High-throughput

0.537

High

635932

PDP2
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

1

1

High-throughput

0.536

High

635993

DNLI4
DNA ligase 4

1

1

High-throughput

0.536

High

511731

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.513

High

635968

MMM1
Maintenance of mitochondrial morphology protein 1

1

0

Small-scale

0.513

High

635977

MDM34
Mitochondrial distribution and morphology protein 34

1

0

Small-scale

0.513

High

432485

RL7A
Large ribosomal subunit protein uL30A

1

1

High-throughput

0.489

High

548665

RNA1
Ran GTPase-activating protein 1

1

1

High-throughput

0.489

High

569713

RL30
Large ribosomal subunit protein eL30

1

1

High-throughput

0.489

High

635929

RS3A2
Small ribosomal subunit protein eS1B

1

2

High-throughput

0.489

High

635936

RL16B
Large ribosomal subunit protein uL13B

1

4

High-throughput

0.489

High

635957

ATG12
Ubiquitin-like protein ATG12

1

1

High-throughput

0.489

High

635958

DBP8
ATP-dependent RNA helicase DBP8

1

1

High-throughput

0.489

High

635960

TEM1
Protein TEM1

1

6

High-throughput

0.489

High

635971

YFI6
Uncharacterized protein YFR016C

1

5

High-throughput

0.489

High

366924

ATPB
ATP synthase subunit beta, mitochondrial

1

5

High-throughput

0.479

High

431977

ATPF
ATP synthase subunit 4, mitochondrial

1

2

High-throughput

0.479

High

439089

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

1

High-throughput

0.479

High

452629

ADH3
Alcohol dehydrogenase 3, mitochondrial

1

1

High-throughput

0.479

High

456329

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

2

High-throughput

0.479

High

514455

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

594181

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

604898

MDHM
Malate dehydrogenase, mitochondrial

1

7

Small-scale

0.479

High

613518

ADT2
ADP,ATP carrier protein 2

1

3

Small-scale

0.479

High

626579

HSP60
Heat shock protein 60, mitochondrial

1

8

High-throughput

0.479

High

635927

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

2

High-throughput

0.479

High

635928

AIM17
Probable oxidoreductase AIM17

1

2

High-throughput

0.479

High

635931

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

2

High-throughput

0.479

High

635933

CDC48
Cell division control protein 48

1

2

High-throughput

0.479

High

635934

KAD3
GTP:AMP phosphotransferase, mitochondrial

1

5

High-throughput

0.479

High

635938

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

2

High-throughput

0.479

High

635939

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

5

High-throughput

0.479

High

635946

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

1

High-throughput

0.479

High

635949

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.479

High

635950

PRX1
Peroxiredoxin PRX1, mitochondrial

1

4

High-throughput

0.479

High

635961

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

1

High-throughput

0.479

High

635963

ALDH5
Aldehyde dehydrogenase 5, mitochondrial

1

6

High-throughput

0.479

High

635964

AIM9
Altered inheritance of mitochondria protein 9, mitochondrial

1

1

High-throughput

0.479

High

635967

COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial

1

1

High-throughput

0.479

High

635970

ETFB
Probable electron transfer flavoprotein subunit beta

1

3

High-throughput

0.479

High

635972

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

6

High-throughput

0.479

High

635975

TOM22
Mitochondrial import receptor subunit TOM22

1

1

High-throughput

0.479

High

635979

SHY1
Cytochrome oxidase assembly protein SHY1

1

1

Small-scale

0.479

High

635981

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

635984

ABF2
ARS-binding factor 2, mitochondrial

1

1

Small-scale

0.479

High

635985

GLRX5
Monothiol glutaredoxin-5, mitochondrial

1

1

High-throughput

0.479

High

635990

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

1

High-throughput

0.479

High

635991

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

1

High-throughput

0.479

High

635945

TOR2
Serine/threonine-protein kinase TOR2

1

0

High-throughput

0.460

High

399911

COX8
Cytochrome c oxidase subunit 8, mitochondrial

1

0

Small-scale

0.458

High

571289

DPOZ
DNA polymerase zeta catalytic subunit

1

0

Small-scale

0.458

High

635954

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

635955

QCR10
Cytochrome b-c1 complex subunit 10, mitochondrial

1

0

Small-scale

0.458

High

635965

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

0

High-throughput

0.458

High

635978

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

635980

ATP23
Mitochondrial inner membrane protease ATP23

1

0

High-throughput

0.458

High

635992

GDE
Glycogen debranching enzyme

1

0

High-throughput

0.458

High

635999

YJ133
Uncharacterized protein YJL133C-A

1

0

High-throughput

0.458

High

525903

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

558580

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.437

High

635930

SIS1
Protein SIS1

1

3

High-throughput

0.437

High

635940

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

635942

HS104
Heat shock protein 104

1

6

Small-scale

0.437

High

635943

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.437

High

635962

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

635974

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

635986

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.437

High

635998

DBP10
ATP-dependent RNA helicase DBP10

1

2

High-throughput

0.437

High

383517

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.407

High

427135

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.407

High

433144

RL17A
Large ribosomal subunit protein uL22A

1

1

High-throughput

0.407

High

434821

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.407

High

531600

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.407

High

543795

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.407

High

569904

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.407

High

592007

VATB
V-type proton ATPase subunit B

1

5

High-throughput

0.407

High

635935

RL16A
Large ribosomal subunit protein uL13A

1

4

High-throughput

0.407

High

635976

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.407

High

635996

RL7B
Large ribosomal subunit protein uL30B

1

1

High-throughput

0.407

High

635952

PTK1
Serine/threonine-protein kinase PTK1/STK1

1

0

High-throughput

0.279

Low

635959

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.279

Low

635982

RL15B
Large ribosomal subunit protein eL15B

1

0

High-throughput

0.279

Low

635997

RPN5
26S proteasome regulatory subunit RPN5

1

0

High-throughput

0.279

Low

635973

MTR4
ATP-dependent RNA helicase DOB1

1

0

High-throughput

0.269

Low

503750

RL27A
Large ribosomal subunit protein eL27A

1

0

High-throughput

0.249

Low

511134

RL20B
Large ribosomal subunit protein eL20B

1

0

High-throughput

0.249

Low

635947

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

635948

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

635951

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

635956

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

635987

PML39
Pre-mRNA leakage protein 39

1

0

High-throughput

0.249

Low

635988

HMO1
High mobility group protein 1

1

0

High-throughput

0.249

Low

635994

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

635937

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.232

Low

635941

RL8B
Large ribosomal subunit protein eL8B

1

0

High-throughput

0.232

Low

635966

RL13B
Large ribosomal subunit protein eL13B

1

0

High-throughput

0.232

Low

635969

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.232

Low

635983

RL6A
Large ribosomal subunit protein eL6A

1

0

High-throughput

0.232

Low

635989

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025