HitPredict

Interactor 1: DNJB1 (P25685)
DnaJ homolog subfamily B member 1 (DnaJ protein homolog 1) (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40) (Human DnaJ protein 1) (hDj-1)
Gene: DNAJB1

Interactor 2: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045296 - cadherin binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 340 Hs			1 248
+	Hs
		636299 DNJB1_HUMAN (1-340): 5.05e-137: 394: 100.00		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	Hs
		927624 DNJB4_HUMAN (1-339): 1.15e-134: 388: 64.60		1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37
+	Zm
		6568 B4F810_MAIZE (1-338): 5.4e-127: 368: 43.64		A0A1D6E930_MAIZE (1-247): 6.82e-142: 400: 55.00
+	Hs
		681397 DNJA1_HUMAN (5-339): 2.97e-117: 346: 32.77		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	At
		788496 DNAJ2_ARATH (5-339): 1.72e-104: 314: 28.45		14333_ARATH (3-247): 2.63e-144: 405: 58.30
+	Hs
		636298 DNJB1_HUMAN (1-340): 5.05e-137: 394: 100.00		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		636318 DNJB1_HUMAN (1-340): 5.05e-137: 394: 100.00		1433F_HUMAN (2-242): 2.78e-96: 283: 64.20
+	Mm
		935670 DNJB4_MOUSE (1-339): 1.2e-132: 383: 62.83		1433F_MOUSE (2-242): 1.72e-96: 284: 64.20
+	Mm
		935616 DJB11_MOUSE (2-338): 1.28e-103: 309: 31.97		1433F_MOUSE (2-242): 1.72e-96: 284: 64.20