HitPredict

Interactor 1: CDC48 (P25694)
Cell division control protein 48 (EC 3.6.4.6) (Cell division cycle protein 48) (Transitional endoplasmic reticulum ATPase homolog)
Gene: CDC48

Interactor 2: UBX7 (P38349)
UBX domain-containing protein 7
Gene: UBX7

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	1.00	0.938

Property	Details
Experiments	15258615, 14755638, 16554755, 37968396, 21211725
Identification Methods	two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	CDC48_2~UBX, CDC48_N~UBX
Common GO terms	GO:0036503 - ERAD pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 835 Sc			1 436
+	Sc
		636664 CDC48_YEAST (1-835): 0: 786: 100.00		UBX6_YEAST (2-382): 4.69e-98: 300: 28.86
+	Hs
		875167 TERA_HUMAN (13-834): 0: 735: 66.79		UBXN4_HUMAN (85-426): 6.57e-70: 231: 18.23
+	Ce
		712422 TERA2_CAEEL (11-804): 0: 717: 66.75		UBXN4_CAEEL (75-427): 6.82e-77: 248: 18.51
+	Ce
		712421 TERA1_CAEEL (11-835): 0: 714: 67.07		UBXN4_CAEEL (75-427): 6.82e-77: 248: 18.51
+	Hs
		875432 TERA_HUMAN (13-834): 0: 735: 66.79		FAF1_HUMAN (44-294): 2.75e-52: 187: 17.67
+	Mm
		872336 TERA_MOUSE (13-834): 0: 735: 66.79		FAF1_MOUSE (44-294): 1.06e-51: 186: 17.29
+	Hs
		875290 TERA_HUMAN (13-834): 0: 735: 66.79		ASPC1_HUMAN (124-368): 6.57e-48: 174: 16.40
+	Hs
		299344 TERA_HUMAN (13-834): 0: 735: 66.79		UBXN7_HUMAN (50-293): 3.23e-43: 160: 12.29
+	Hs
		116676 TERA_HUMAN (13-834): 0: 735: 66.79		UBXN8_HUMAN (107-297): 5.09e-39: 143: 14.95
+	Mm
		967687 TERA_MOUSE (13-834): 0: 735: 66.79		UBXN1_MOUSE (72-296): 1.39e-38: 143: 19.25
+	Hs
		874846 TERA_HUMAN (13-834): 0: 735: 66.79		UBXN1_HUMAN (94-296): 8.23e-36: 135: 19.81
+	Ce
		873015 TERA2_CAEEL (11-804): 0: 717: 66.75		UBXN1_CAEEL (86-291): 3.45e-40: 147: 18.93
+	Sc
		636779 CDC48_YEAST (1-835): 0: 786: 100.00		UBX3_YEAST (54-291): 7.12e-12: 68.9: 11.28
+	Hs
		875209 TERA_HUMAN (13-834): 0: 735: 66.79		FAF2_HUMAN (5-293): 1.13e-14: 77.4: 13.03
+	Dm
		1180101 TERA_DROME (16-835): 0: 736: 67.07		Q7K4I5_DROME (50-290): 9.86e-13: 71.6: 11.11
+	At
		67566 CD48A_ARATH (8-809): 0: 736: 66.25		A8MRM0_ARATH (49-285): 4.82e-11: 66.2: 13.71
+	At
		870959 CD48A_ARATH (8-809): 0: 736: 66.25		PUX7_ARATH (49-285): 5.54e-11: 66.2: 13.71
+	Rn
		472980 TERA_RAT (13-834): 0: 735: 66.79		UBX2B_RAT (123-294): 5.35e-11: 65.4: 15.00
+	Hs
		874941 TERA_HUMAN (13-834): 0: 735: 66.79		UBX2B_HUMAN (123-294): 4.72e-10: 62.7: 15.56
+	Hs
		875291 TERA_HUMAN (13-834): 0: 735: 66.79		UBXN6_HUMAN (127-288): 5.98e-09: 59.7: 14.82