HitPredict

Interactor 1: VATC1 (P21283)
V-type proton ATPase subunit C 1 (V-ATPase subunit C 1) (Vacuolar proton pump subunit C 1)
Gene: ATP6V1C1

Interactor 2: VATH (Q9UI12)
V-type proton ATPase subunit H (V-ATPase subunit H) (Nef-binding protein 1) (NBP1) (Protein VMA13 homolog) (V-ATPase 50/57 kDa subunits) (Vacuolar proton pump subunit H) (Vacuolar proton pump subunit SFD)
Gene: ATP6V1H

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 35271311, 40437099
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains V-ATPase_C~V-ATPase_H_C
Common GO terms GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0016241 - regulation of macroautophagy
and 5 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 382
Hs

1 483
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025