HitPredict

Interactor 1: PSA4 (P25789)
Proteasome subunit alpha type-4 (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome component C9) (Proteasome subunit L)
Gene: PSMA4

Interactor 2: RD23B (P54727)
UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)
Gene: RAD23B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 261 Hs			1 409
+	Rn
		599953 PSA4_RAT (1-237): 3.97e-98: 289: 99.58		RD23B_RAT (1-409): 1.14e-120: 358: 87.23
+	Hs
		872245 PSA6_HUMAN (2-244): 3.23e-92: 273: 31.84		RD23B_HUMAN (1-409): 1.31e-125: 370: 100.00
+	Hs
		637370 PSA1_HUMAN (4-259): 2.5e-91: 272: 28.57		RD23B_HUMAN (1-409): 1.31e-125: 370: 100.00
+	Hs
		638095 PSA4_HUMAN (1-237): 2.4e-98: 289: 100.00		RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72
+	Hs
		872130 PSA6_HUMAN (2-244): 3.23e-92: 273: 31.84		RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72
+	Hs
		637369 PSA1_HUMAN (4-259): 2.5e-91: 272: 28.57		RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72
+	Hs
		638217 PSA4_HUMAN (1-237): 2.4e-98: 289: 100.00		UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72
+	Hs
		893771 PSA6_HUMAN (2-244): 3.23e-92: 273: 31.84		UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72
+	Hs
		638212 PSA4_HUMAN (1-237): 2.4e-98: 289: 100.00		UBQL2_HUMAN (1-364): 5.93e-51: 182: 13.68
+	Hs
		638204 PSA4_HUMAN (1-237): 2.4e-98: 289: 100.00		UBQL4_HUMAN (1-364): 2.75e-45: 166: 12.71
+	Hs
		893768 PSA6_HUMAN (2-244): 3.23e-92: 273: 31.84		UBQL2_HUMAN (1-364): 5.93e-51: 182: 13.68
+	Hs
		893761 PSA6_HUMAN (2-244): 3.23e-92: 273: 31.84		UBQL4_HUMAN (1-364): 2.75e-45: 166: 12.71
+	Hs
		637575 PSA1_HUMAN (4-259): 2.5e-91: 272: 28.57		UBQL4_HUMAN (1-364): 2.75e-45: 166: 12.71
+	Hs
		474931 PSA4_HUMAN (1-237): 2.4e-98: 289: 100.00		UBB_HUMAN (1-79): 1.99e-32: 123: 30.38
+	At
		286456 PSA4A_ARATH (1-248): 8.93e-98: 288: 58.40		UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75
+	Hs
		893646 PSA6_HUMAN (2-244): 3.23e-92: 273: 31.84		RL40_HUMAN (1-91): 3.57e-33: 122: 28.57
+	Hs
		637386 PSA1_HUMAN (4-259): 2.5e-91: 272: 28.57		RL40_HUMAN (1-91): 3.57e-33: 122: 28.57
+	Hs
		638108 PSA4_HUMAN (1-237): 2.4e-98: 289: 100.00		RS27A_HUMAN (1-90): 2.4e-15: 75: 26.67
+	Hs
		893645 PSA6_HUMAN (2-244): 3.23e-92: 273: 31.84		RS27A_HUMAN (1-90): 2.4e-15: 75: 26.67
+	Hs
		637385 PSA1_HUMAN (4-259): 2.5e-91: 272: 28.57		RS27A_HUMAN (1-90): 2.4e-15: 75: 26.67