HitPredict

Interactor 1: PSA4 (P25789)
Proteasome subunit alpha type-4 (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome component C9) (Proteasome subunit L)
Gene: PSMA4

Interactor 2: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 261 Hs			1 156
+	Hs
		893645 PSA6_HUMAN (2-244): 3.23e-92: 273: 31.84		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		637385 PSA1_HUMAN (4-259): 2.5e-91: 272: 28.57		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Rn
		576260 PSA1_RAT (4-259): 2.85e-105: 307: 28.19		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	Hs
		893646 PSA6_HUMAN (2-244): 3.23e-92: 273: 31.84		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	At
		286456 PSA4A_ARATH (1-248): 8.93e-98: 288: 58.40		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Hs
		474931 PSA4_HUMAN (1-237): 2.4e-98: 289: 100.00		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00
+	Hs
		637386 PSA1_HUMAN (4-259): 2.5e-91: 272: 28.57		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Rn
		893780 PSA6_RAT (2-244): 3.23e-92: 273: 31.84		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	Mm
		477050 PSA1_MOUSE (4-259): 5.8e-88: 263: 28.57		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	At
		672527 PSA7A_ARATH (3-237): 3.81e-91: 271: 36.02		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		286449 PSA6A_ARATH (2-244): 4.58e-91: 270: 31.84		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		189234 PSA7B_ARATH (3-237): 6.52e-88: 263: 36.02		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		286452 PSA6B_ARATH (2-244): 1.42e-86: 259: 30.61		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Sc
		408276 PSA2_YEAST (1-220): 3.05e-39: 138: 38.01		RS31_YEAST (1-151): 4.55e-61: 187: 82.78
+	Rn
		566254 PSA2_RAT (3-214): 4.43e-42: 145: 38.68		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	At
		1091773 PSA2B_ARATH (4-241): 5.86e-44: 150: 38.66		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		188696 PSA2A_ARATH (4-241): 6.12e-44: 150: 38.66		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Hs
		474930 PSA2_HUMAN (3-214): 6.04e-42: 145: 38.68		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00