HitPredict

Interactor 1: PSA4 (P25789)
Proteasome subunit alpha type-4 (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome component C9) (Proteasome subunit L)
Gene: PSMA4

Interactor 2: PSMF1 (Q92530)
Proteasome inhibitor PI31 subunit (hPI31)
Gene: PSMF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005839 - proteasome core complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 261 Hs			1 271
+	Hs
		108949 H0YKT8_HUMAN (25-205): 1.07e-132: 374: 100.00		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		893716 PSA6_HUMAN (2-244): 3.23e-92: 273: 31.84		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		637501 PSA1_HUMAN (4-259): 2.5e-91: 272: 28.57		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		156330 PSA7_HUMAN (5-238): 2.84e-91: 271: 33.19		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Dm
		574035 PSA4_DROME (1-242): 9.91e-93: 275: 72.25		PSMF1_DROME (3-270): 5e-108: 315: 29.46
+	Hs
		637723 PSA2_HUMAN (3-214): 6.04e-42: 145: 38.68		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		893684 PSA6_HUMAN (2-244): 3.23e-92: 273: 31.84		Q5QPM9_HUMAN (1-183): 1.97e-104: 302: 100.00
+	Dm
		1360134 PSA6_DROME (2-244): 2.34e-86: 258: 29.10		PSMF1_DROME (3-270): 5e-108: 315: 29.46