HitPredict

Interactor 1: SPB4 (P25808)
ATP-dependent rRNA helicase SPB4 (EC 3.6.4.13) (Suppressor of PAB1 protein 4)
Gene: SPB4

Interactor 2: UFD4 (P33202)
Ubiquitin fusion degradation protein 4 (UB fusion protein 4) (EC 2.3.2.-) (HECT-type E3 ubiquitin transferase UFD4) (EC 2.3.2.26)
Gene: UFD4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	21825077
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 606 Sc			1 1483
+	Hs
		125749 DDX18_HUMAN (6-467): 8.02e-159: 472: 29.61		WWP2_HUMAN (610-1480): 0: 722: 16.39
+	Hs
		125617 DDX17_HUMAN (2-463): 7.88e-127: 391: 21.89		WWP2_HUMAN (610-1480): 0: 722: 16.39
+	Hs
		125142 DDX5_HUMAN (2-454): 2.38e-125: 384: 22.34		WWP2_HUMAN (610-1480): 0: 722: 16.39
+	Ce
		1325774 Q9N3F4_CAEEL (7-395): 6.81e-148: 443: 30.69		Q9GUP2_CAEEL (504-1483): 0: 603: 14.31
+	Sc
		975806 HAS1_YEAST (6-467): 1.01e-156: 460: 30.98		TOM1_YEAST (595-1483): 1.37e-167: 562: 16.87
+	Ce
		1145732 Q65XX1_CAEEL (7-395): 1.21e-147: 443: 30.69		WWP1_CAEEL (885-1480): 0: 571: 18.50
+	Ce
		1280088 Q95XY1_CAEEL (7-395): 7.47e-148: 443: 30.69		WWP1_CAEEL (885-1480): 0: 571: 18.50
+	Ce
		1341503 Q9N3F4_CAEEL (7-395): 6.81e-148: 443: 30.69		WWP1_CAEEL (885-1480): 0: 571: 18.50
+	Sc
		765376 HAS1_YEAST (6-467): 1.01e-156: 460: 30.98		RSP5_YEAST (774-1480): 1.01e-176: 550: 15.57
+	Hs
		1336092 DDX18_HUMAN (6-467): 8.02e-159: 472: 29.61		SMUF1_HUMAN (965-1479): 4.08e-162: 509: 17.15
+	Sc
		416067 DED1_YEAST (3-402): 8.68e-139: 418: 25.55		TOM1_YEAST (595-1483): 1.37e-167: 562: 16.87
+	Sc
		624167 DBP2_YEAST (2-402): 7.47e-126: 383: 25.43		TOM1_YEAST (595-1483): 1.37e-167: 562: 16.87
+	Hs
		571603 DDX5_HUMAN (2-454): 2.38e-125: 384: 22.34		SMUF1_HUMAN (965-1479): 4.08e-162: 509: 17.15
+	Hs
		1346780 DDX18_HUMAN (6-467): 8.02e-159: 472: 29.61		HECD1_HUMAN (1277-1475): 3.61e-27: 123: 35.44
+	Hs
		983249 DDX18_HUMAN (6-467): 8.02e-159: 472: 29.61		UBE3A_HUMAN (1204-1482): 2.39e-21: 103: 29.17
+	Hs
		1183374 DDX46_HUMAN (2-597): 8.55e-134: 418: 21.15		HECD1_HUMAN (1277-1475): 3.61e-27: 123: 35.44
+	Hs
		1183325 DDX46_HUMAN (2-597): 8.55e-134: 418: 21.15		HUWE1_HUMAN (1191-1483): 1.44e-20: 101: 31.51
+	Hs
		1271692 DDX17_HUMAN (2-463): 7.88e-127: 391: 21.89		HECD1_HUMAN (1277-1475): 3.61e-27: 123: 35.44
+	Hs
		571631 DDX5_HUMAN (2-454): 2.38e-125: 384: 22.34		HECD1_HUMAN (1277-1475): 3.61e-27: 123: 35.44
+	Hs
		1245891 DDX55_HUMAN (6-594): 5.25e-122: 375: 34.05		HECD1_HUMAN (1277-1475): 3.61e-27: 123: 35.44