HitPredict

Interactor 1: SPB4 (P25808)
ATP-dependent rRNA helicase SPB4 (EC 3.6.4.13) (Suppressor of PAB1 protein 4)
Gene: SPB4

Interactor 2: NOG2 (P53742)
Nucleolar GTP-binding protein 2
Gene: NOG2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	37811893, 30568249, 21825077
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 606 Sc			1 486
+	Sc
		864672 HAS1_YEAST (6-467): 1.01e-156: 460: 30.98		NOG2_YEAST (1-467): 0: 530: 100.00
+	Hs
		1045708 DDX18_HUMAN (6-467): 8.02e-159: 472: 29.61		NOG2_HUMAN (4-472): 6.46e-161: 475: 52.87
+	Dm
		1177944 DDX18_DROME (6-481): 1.03e-152: 457: 28.96		Q7JXU4_DROME (11-482): 1.59e-152: 451: 48.33
+	Hs
		1045613 DDX46_HUMAN (2-597): 8.55e-134: 418: 21.15		NOG2_HUMAN (4-472): 6.46e-161: 475: 52.87
+	Hs
		1045635 DDX55_HUMAN (6-594): 5.25e-122: 375: 34.05		NOG2_HUMAN (4-472): 6.46e-161: 475: 52.87
+	Hs
		1314090 DDX18_HUMAN (6-467): 8.02e-159: 472: 29.61		GNL3_HUMAN (84-482): 2.27e-106: 329: 27.57
+	Sc
		859626 HAS1_YEAST (6-467): 1.01e-156: 460: 30.98		LSG1_YEAST (97-484): 1.98e-100: 316: 21.09
+	Dm
		1229284 DDX18_DROME (6-481): 1.03e-152: 457: 28.96		GNL3_DROME (89-475): 6.14e-97: 305: 27.49
+	Sc
		766689 HAS1_YEAST (6-467): 1.01e-156: 460: 30.98		NUG1_YEAST (91-483): 1.8e-90: 287: 24.71
+	Sc
		638763 SPB4_YEAST (1-606): 2.46e-149: 445: 100.00		NUG1_YEAST (91-483): 1.8e-90: 287: 24.71
+	Sc
		699707 DRS1_YEAST (21-392): 3.9e-47: 178: 31.75		NOG2_YEAST (1-467): 0: 530: 100.00
+	Sc
		624135 DBP2_YEAST (2-402): 7.47e-126: 383: 25.43		LSG1_YEAST (97-484): 1.98e-100: 316: 21.09
+	Hs
		134190 DDX3X_HUMAN (4-406): 1.31e-116: 363: 24.40		GNL3_HUMAN (84-482): 2.27e-106: 329: 27.57
+	Dm
		1177948 DDX47_DROME (3-376): 3.85e-54: 194: 33.87		Q7JXU4_DROME (11-482): 1.59e-152: 451: 48.33
+	Dm
		1177939 Y8611_DROME (23-437): 5.36e-47: 179: 29.23		Q7JXU4_DROME (11-482): 1.59e-152: 451: 48.33
+	Sc
		638841 SPB4_YEAST (1-606): 2.46e-149: 445: 100.00		MTG1_YEAST (196-413): 1.48e-40: 151: 22.31
+	Dm
		1229288 DDX47_DROME (3-376): 3.85e-54: 194: 33.87		GNL3_DROME (89-475): 6.14e-97: 305: 27.49
+	Sc
		699686 DRS1_YEAST (21-392): 3.9e-47: 178: 31.75		NUG1_YEAST (91-483): 1.8e-90: 287: 24.71