HitPredict

Interactor 1: SPB4 (P25808)
ATP-dependent rRNA helicase SPB4 (EC 3.6.4.13) (Suppressor of PAB1 protein 4)
Gene: SPB4

Interactor 2: IPI3 (P53877)
Pre-rRNA-processing protein IPI3 (Involved in processing IST2 protein 3)
Gene: IPI3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	36929751, 21825077
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000027 - ribosomal large subunit assembly GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 606 Sc			1 555
+	Hs
		903549 DDX18_HUMAN (6-467): 8.02e-159: 472: 29.61		WDR5_HUMAN (2-287): 3.87e-43: 158: 13.06
+	Sc
		630886 HAS1_YEAST (6-467): 1.01e-156: 460: 30.98		NLE1_YEAST (2-284): 6.92e-39: 151: 9.69
+	Sc
		630846 SPB4_YEAST (1-606): 2.46e-149: 445: 100.00		NLE1_YEAST (2-284): 6.92e-39: 151: 9.69
+	Hs
		903327 DDX46_HUMAN (2-597): 8.55e-134: 418: 21.15		WDR5_HUMAN (2-287): 3.87e-43: 158: 13.06
+	Hs
		903410 DDX17_HUMAN (2-463): 7.88e-127: 391: 21.89		WDR5_HUMAN (2-287): 3.87e-43: 158: 13.06
+	Hs
		571382 DDX5_HUMAN (2-454): 2.38e-125: 384: 22.34		WDR5_HUMAN (2-287): 3.87e-43: 158: 13.06
+	Sc
		416039 DED1_YEAST (3-402): 8.68e-139: 418: 25.55		COPA_YEAST (5-320): 4.48e-27: 118: 10.62
+	Sc
		635633 HAS1_YEAST (6-467): 1.01e-156: 460: 30.98		PWP2_YEAST (3-320): 5.66e-09: 61.1: 9.66
+	Hs
		133956 DDX3X_HUMAN (4-406): 1.31e-116: 363: 24.40		WDR5_HUMAN (2-287): 3.87e-43: 158: 13.06
+	Sc
		635549 SPB4_YEAST (1-606): 2.46e-149: 445: 100.00		PWP2_YEAST (3-320): 5.66e-09: 61.1: 9.66
+	Hs
		1271679 DDX17_HUMAN (2-463): 7.88e-127: 391: 21.89		NLE1_HUMAN (425-533): 6.69e-20: 94.6: 10.09
+	Sc
		415901 DED1_YEAST (3-402): 8.68e-139: 418: 25.55		PWP2_YEAST (3-320): 5.66e-09: 61.1: 9.66
+	Hs
		903507 DDX47_HUMAN (23-382): 7.93e-54: 191: 34.35		WDR5_HUMAN (2-287): 3.87e-43: 158: 13.06
+	Sc
		630853 DRS1_YEAST (21-392): 3.9e-47: 178: 31.75		NLE1_YEAST (2-284): 6.92e-39: 151: 9.69
+	Hs
		1070052 DDX41_HUMAN (18-394): 1.19e-47: 178: 30.95		PWP2_HUMAN (139-526): 1.12e-33: 138: 13.33
+	Sc
		593593 DBP4_YEAST (21-467): 7e-51: 189: 31.36		PWP2_YEAST (3-320): 5.66e-09: 61.1: 9.66