HitPredict

Interactor 1: CKB11 (P25859)
Cyclin-dependent kinase B1-1 (CDKB1;1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog B)
Gene: CDKB1-1

Interactor 2: CKS2 (Q9SJJ5)
Cyclin-dependent kinases regulatory subunit 2
Gene: CKS2

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.863

Property	Details
Experiments	17426018, 20407024, 20706207
Identification Methods	affinity chromatography technology, protein complementation assay, two hybrid, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	CKS~Pkinase
Common GO terms	GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 309 At			1 83
+	At
		1103378 CKB12_ARATH (1-309): 1.09e-139: 398: 87.78		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	At
		621728 CDKA1_ARATH (1-304): 4.3e-135: 386: 54.43		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	At
		188147 CKB12_ARATH (1-309): 1.09e-139: 398: 87.78		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	At
		1227962 CKB21_ARATH (1-308): 3.42e-134: 384: 64.94		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	At
		1228093 CKB22_ARATH (1-308): 3.85e-133: 382: 64.94		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	At
		188137 CKB11_ARATH (1-309): 3.71e-138: 394: 100.00		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	At
		188136 CDKA1_ARATH (1-304): 4.3e-135: 386: 54.43		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	Hs
		625283 CDK2_HUMAN (1-307): 1.5e-139: 397: 53.25		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	At
		188156 CKB21_ARATH (1-308): 3.42e-134: 384: 64.94		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	At
		188157 CKB22_ARATH (1-308): 3.85e-133: 382: 64.94		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	Hs
		625164 CDK2_HUMAN (1-307): 1.5e-139: 397: 53.25		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22
+	Hs
		895413 CDK3_HUMAN (1-307): 5.16e-136: 388: 56.17		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	At
		1321299 CDKD1_ARATH (2-305): 2.32e-123: 360: 39.47		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	Hs
		706796 CDK3_HUMAN (1-307): 5.16e-136: 388: 56.17		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22
+	Hs
		414843 CDK1_HUMAN (1-306): 3.13e-132: 378: 52.12		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	Hs
		414778 CDK1_HUMAN (1-306): 3.13e-132: 378: 52.12		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22
+	Dm
		618415 CDK1_DROME (1-305): 9.45e-127: 365: 51.63		Q9VHN1_DROME (2-71): 2.92e-37: 121: 65.71
+	Hs
		895414 CDK5_HUMAN (1-307): 9.57e-127: 365: 50.49		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	Dm
		618387 CDK1_DROME (1-305): 9.45e-127: 365: 51.63		CKS1_DROME (3-71): 4.92e-35: 115: 68.12
+	Hs
		706797 CDK5_HUMAN (1-307): 9.57e-127: 365: 50.49		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22