HitPredict

Interactor 1: CDC20 (P26309)
APC/C activator protein CDC20 (Cell division control protein 20)
Gene: CDC20

Interactor 2: HSL1 (P34244)
Probable serine/threonine-protein kinase HSL1 (EC 2.7.11.1)
Gene: HSL1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.713

Property	Details
Experiments	10848588, 11562348, 17369399, 28189585
Identification Methods	two hybrid, coimmunoprecipitation, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 610 Sc			1 1518
+	Sc
		710979 CDH1_YEAST (111-557): 2.02e-98: 313: 28.76		HSL1_YEAST (1-1518): 0: 1269: 100.00
+	Hs
		1281519 FBXW7_HUMAN (329-608): 1.28e-60: 216: 14.54		MRCKB_HUMAN (72-1152): 5.9e-147: 494: 16.82
+	Hs
		1281380 FBXW7_HUMAN (329-608): 1.28e-60: 216: 14.54		SIK2_HUMAN (72-946): 5.48e-132: 434: 21.95
+	Hs
		1025190 FBXW7_HUMAN (329-608): 1.28e-60: 216: 14.54		AAPK1_HUMAN (62-630): 1.1e-135: 432: 23.12
+	Hs
		1254745 FBXW7_HUMAN (329-608): 1.28e-60: 216: 14.54		BRSK1_HUMAN (78-808): 1.6e-130: 426: 27.20
+	Hs
		1219186 FZR1_HUMAN (391-606): 5.47e-17: 86.2: 13.18		BRSK2_HUMAN (63-644): 6.16e-131: 425: 31.08
+	Sc
		419809 NLE1_YEAST (508-610): 1.58e-11: 68.9: 12.50		SNF1_YEAST (61-576): 8.87e-122: 397: 26.95