HitPredict

Interactor 1: DNMT1 (P26358)
DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (CXXC-type zinc finger protein 9) (DNA methyltransferase HsaI) (DNA MTase HsaI) (M.HsaI) (MCMT)
Gene: DNMT1

Interactor 2: H33 (P84243)
Histone H3.3
Gene: H3-3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36089195
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1616 Hs			1 136
+	Hs
		641190 DNMT1_HUMAN (1-1616): 0: 1717: 100.00		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		641229 DNMT1_HUMAN (1-1616): 0: 1717: 100.00		H31T_HUMAN (1-136): 2.58e-59: 181: 93.38
+	Hs
		641169 DNMT1_HUMAN (1-1616): 0: 1717: 100.00		CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76
+	Xl
		945537 P79922_XENLA (126-1616): 0: 1502: 70.07		H33_XENLA (1-136): 1.12e-59: 182: 100.00
+	Xl
		945601 P79922_XENLA (126-1616): 0: 1502: 70.07		Q92133_XENLA (1-136): 2.72e-59: 181: 96.32
+	Xl
		945420 P79922_XENLA (126-1616): 0: 1502: 70.07		H32_XENLA (1-136): 5.32e-59: 180: 97.06
+	Hs
		934930 PB1_HUMAN (42-1162): 0: 602: 15.37		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		952441 PB1_HUMAN (42-1162): 0: 602: 15.37		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Hs
		1086201 PB1_HUMAN (42-1162): 0: 602: 15.37		H31T_HUMAN (1-136): 2.58e-59: 181: 93.38
+	Hs
		828285 PB1_HUMAN (42-1162): 0: 602: 15.37		CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76
+	Nc
		421242 Q3Y3Z1_NEUCR (1040-1604): 1.28e-120: 416: 22.53		H3_NEUCR (1-135): 6.88e-57: 175: 91.85
+	Hs
		935328 DNM3B_HUMAN (1130-1325): 2.44e-41: 167: 17.65		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		935380 SMC3_HUMAN (112-523): 4.15e-40: 164: 12.53		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		952703 SMC3_HUMAN (112-523): 4.15e-40: 164: 12.53		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Hs
		1174693 SMC3_HUMAN (112-523): 4.15e-40: 164: 12.53		H32_HUMAN (1-136): 5.32e-59: 180: 97.06
+	Mm
		291727 DNM3A_MOUSE (1128-1326): 6.78e-37: 153: 17.87		H33_MOUSE (1-136): 1.12e-59: 182: 100.00
+	Hs
		935442 DNM3A_HUMAN (1128-1326): 1.35e-36: 152: 17.87		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		952734 DNM3A_HUMAN (1128-1326): 1.35e-36: 152: 17.87		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Hs
		935150 MINT_HUMAN (5-706): 1.98e-35: 150: 12.71		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		828439 DNM3A_HUMAN (1128-1326): 1.35e-36: 152: 17.87		CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76