Interactor 1: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Interactor 2: SF01 (Q15637)
Splicing factor 1 (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162)
Gene: SF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 26641092, 32296183, 35271311, 22365833, 16189514, 9512519, 9150140, 23273425, 26420826, 12718882, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, pull down, isothermal titration calorimetry, x ray scattering, x-ray crystallography, nuclear magnetic resonance, dynamic light scattering, molecular sieving, anti bait coimmunoprecipitation and 6 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RRM_1~SF1-HH
Common GO terms GO:0000245 - spliceosomal complex assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 2 others

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Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 475
Hs

1 639
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Last updated: 15 Jul 2024