HitPredict

Interactor 1: U2AF2 (P26369)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Interactor 2: EED (Q921E6)
Polycomb protein EED
Gene: EED

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 475 Mm			1 441
+	Hs
		267900 U2AF2_HUMAN (1-475): 8.01e-89: 281: 99.79		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		1257587 RBM39_MOUSE (145-471): 1.26e-48: 176: 18.23		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		268085 RBM39_HUMAN (145-471): 1.24e-48: 176: 18.23		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		641882 U2AF2_HUMAN (1-475): 8.01e-89: 281: 99.79		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Mm
		1112470 PUF60_MOUSE (92-474): 1.77e-22: 102: 20.43		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		268323 PUF60_HUMAN (92-474): 3.07e-22: 101: 20.67		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		665768 PABP1_MOUSE (4-260): 2.19e-19: 93.1: 14.93		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		641889 U2AF2_HUMAN (1-475): 8.01e-89: 281: 99.79		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		903236 SART3_HUMAN (10-376): 3.06e-87: 288: 22.58		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		641697 U2AF2_HUMAN (1-475): 8.01e-89: 281: 99.79		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		197022 SART3_HUMAN (10-376): 3.06e-87: 288: 22.58		PRP4_HUMAN (337-437): 3.12e-09: 60.7: 16.51
+	Hs
		196958 U2AF2_HUMAN (1-475): 8.01e-89: 281: 99.79		PRP4_HUMAN (337-437): 3.12e-09: 60.7: 16.51
+	Hs
		1054489 RBM39_HUMAN (145-471): 1.24e-48: 176: 18.23		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		1054500 RBM39_HUMAN (145-471): 1.24e-48: 176: 18.23		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		197019 RBM39_HUMAN (145-471): 1.24e-48: 176: 18.23		PRP4_HUMAN (337-437): 3.12e-09: 60.7: 16.51
+	Hs
		1281457 PUF60_HUMAN (92-474): 3.07e-22: 101: 20.67		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		903585 PUF60_HUMAN (92-474): 3.07e-22: 101: 20.67		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		516438 PABP1_HUMAN (4-260): 2.21e-19: 93.1: 14.93		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		516733 PABP1_HUMAN (4-260): 2.21e-19: 93.1: 14.93		FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97
+	Hs
		903196 PABP4_HUMAN (4-252): 1.04e-17: 88: 13.08		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09