HitPredict

Interactor 1: KRA59 (P26371)
Keratin-associated protein 5-9 (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (Keratin-associated protein 5.9) (UHS keratin A) (UHS KerA) (Ultrahigh sulfur keratin-associated protein 5.9)
Gene: KRTAP5-9

Interactor 2: OTX1 (P32242)
Homeobox protein OTX1 (Orthodenticle homolog 1)
Gene: OTX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.50	0.616

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 169 Hs			1 354
+	Hs
		686492 KRA13_HUMAN (8-166): 8.07e-21: 85.5: 26.25		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		686424 KR109_HUMAN (39-168): 9.93e-17: 77.1: 26.14		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		686421 KR105_HUMAN (6-165): 3.51e-16: 75.5: 26.06		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		686420 KR103_HUMAN (22-166): 2.09e-16: 75.1: 26.12		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		686434 KRA11_HUMAN (31-167): 3.12e-15: 71.3: 30.44		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		686509 KR412_HUMAN (35-166): 1.04e-14: 70.1: 33.33		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		686525 KRA15_HUMAN (3-165): 1.02e-14: 69.7: 21.30		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		686423 KR108_HUMAN (26-165): 4.36e-14: 69.4: 28.87		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		686425 KR10B_HUMAN (2-160): 2.04e-13: 68.2: 23.60		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		686514 KRA92_HUMAN (47-166): 3.82e-14: 68.2: 34.71		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		686516 KRA41_HUMAN (60-166): 8.69e-14: 66.7: 37.96		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		686419 KR101_HUMAN (7-162): 7.55e-13: 66.3: 28.30		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		686513 KRA93_HUMAN (63-166): 1.18e-12: 64: 29.81		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		686515 KR411_HUMAN (1-131): 4.08e-12: 63.2: 25.19		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		686517 KRA47_HUMAN (1-112): 1.97e-12: 63.2: 24.11		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		686518 KRA45_HUMAN (7-160): 5.89e-12: 62.4: 26.04		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		686519 KRA44_HUMAN (1-127): 4.34e-12: 62.4: 29.13		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		686512 KRA94_HUMAN (62-166): 1.31e-11: 60.9: 31.19		OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00
+	Hs
		1077277 KRA44_HUMAN (1-127): 4.34e-12: 62.4: 29.13		ALX1_HUMAN (2-200): 1.96e-36: 136: 24.62
+	Hs
		641554 KRA93_HUMAN (63-166): 1.18e-12: 64: 29.81		PAX6_HUMAN (5-246): 2.79e-31: 124: 23.14