HitPredict

Interactor 1: RAE2 (P26374)
Rab proteins geranylgeranyltransferase component A 2 (Choroideremia-like protein) (Rab escort protein 2) (REP-2)
Gene: CHML

Interactor 2: RB11A (P62491)
Ras-related protein Rab-11A (Rab-11) (EC 3.6.5.2) (YL8)
Gene: RAB11A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.922

Property	Details
Experiments	28514442, 29568061, 34079125, 33961781, 37232246
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005829 - cytosol GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 656 Hs			1 216
+	Hs
		642730 RAE2_HUMAN (1-656): 0: 980: 100.00		RB11B_HUMAN (1-216): 2.54e-91: 268: 90.37
+	Hs
		642723 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB1A_HUMAN (1-213): 1.31e-90: 266: 44.60
+	Hs
		642743 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB1B_HUMAN (4-213): 1.82e-87: 258: 46.19
+	Hs
		642716 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB25_HUMAN (2-190): 8.31e-87: 256: 67.20
+	Hs
		622576 RAE1_HUMAN (1-652): 0: 946: 71.98		RB11A_HUMAN (1-216): 2.38e-94: 276: 100.00
+	Hs
		622590 RAE1_HUMAN (1-652): 0: 946: 71.98		RB11B_HUMAN (1-216): 2.54e-91: 268: 90.37
+	Hs
		622577 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB1A_HUMAN (1-213): 1.31e-90: 266: 44.60
+	Hs
		622619 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB1B_HUMAN (4-213): 1.82e-87: 258: 46.19
+	Hs
		642736 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB2B_HUMAN (8-178): 6.71e-61: 191: 55.56
+	Hs
		622604 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB2B_HUMAN (8-178): 6.71e-61: 191: 55.56
+	Sc
		750738 GDI1_YEAST (176-597): 4.18e-144: 428: 23.72		YPT31_YEAST (1-213): 1.09e-98: 287: 60.54
+	Hs
		678343 GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49		RB11A_HUMAN (1-216): 2.38e-94: 276: 100.00
+	Hs
		838624 GDIB_HUMAN (221-606): 7.43e-140: 417: 21.52		RB11A_HUMAN (1-216): 2.38e-94: 276: 100.00
+	Hs
		678359 GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49		RB11B_HUMAN (1-216): 2.54e-91: 268: 90.37
+	Mm
		838709 GDIA_MOUSE (167-599): 1.13e-141: 422: 20.49		RAB1A_MOUSE (1-213): 1.31e-90: 266: 44.60
+	Hs
		678344 GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49		RAB1A_HUMAN (1-213): 1.31e-90: 266: 44.60
+	Sc
		765614 GDI1_YEAST (176-597): 4.18e-144: 428: 23.72		YPT32_YEAST (7-213): 3.28e-86: 255: 61.50
+	Hs
		678394 GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49		RAB1B_HUMAN (4-213): 1.82e-87: 258: 46.19
+	Hs
		838614 GDIB_HUMAN (221-606): 7.43e-140: 417: 21.52		RAB25_HUMAN (2-190): 8.31e-87: 256: 67.20
+	Hs
		678377 GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49		RAB2B_HUMAN (8-178): 6.71e-61: 191: 55.56