Protein: GCN20
Protein GCN20 (General control non-derepressible protein 20)

Gene: GCN20
Organism: Saccharomyces cerevisiae S288C
Interactions: 124
UniProt ID: P43535

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0006448 - regulation of translational elongation
GO:0016887 - ATP hydrolysis activity
GO:0022626 - cytosolic ribosome
GO:0031369 - translation initiation factor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

707879

GCN1
eIF-2-alpha kinase activator GCN1

8

7

Small-scale

0.756

High

548537

GCN2
eIF-2-alpha kinase GCN2

2

1

Small-scale

0.629

High

561005

EF3A
Elongation factor 3A

1

5

High-throughput

0.618

High

752844

SYNC
Asparagine--tRNA ligase, cytoplasmic

2

5

High-throughput

0.611

High

796954

RUVB2
RuvB-like protein 2

2

6

High-throughput

0.611

High

632578

RAD51
DNA repair protein RAD51

2

1

High-throughput

0.588

High

503009

SEC7
Protein transport protein SEC7

2

1

High-throughput

0.567

High

420506

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD

2

0

High-throughput

0.563

High

511729

SSB1
Ribosome-associated molecular chaperone SSB1

2

8

High-throughput

0.552

High

602700

MCK1
Protein kinase MCK1

1

1

High-throughput

0.501

High

752142

KSP1
Serine/threonine-protein kinase KSP1

1

1

High-throughput

0.501

High

440055

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

6

High-throughput

0.489

High

763166

FHP
Flavohemoprotein

1

2

High-throughput

0.489

High

785071

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.489

High

796911

SA155
SIT4-associating protein SAP155

1

1

High-throughput

0.489

High

796921

BRE5
UBP3-associated protein BRE5

1

4

High-throughput

0.489

High

796929

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

6

High-throughput

0.489

High

796935

GCN5
Histone acetyltransferase GCN5

1

8

High-throughput

0.489

High

703664

PRS6A
26S proteasome regulatory subunit 6A

1

3

High-throughput

0.481

High

752798

SYSM
Serine--tRNA ligase, mitochondrial

1

5

High-throughput

0.481

High

366472

HSP82
ATP-dependent molecular chaperone HSP82

1

8

High-throughput

0.479

High

389105

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

5

High-throughput

0.479

High

543939

HSC82
ATP-dependent molecular chaperone HSC82

1

8

High-throughput

0.479

High

546186

SYKC
Lysine--tRNA ligase, cytoplasmic

1

5

High-throughput

0.479

High

680799

HS104
Heat shock protein 104

1

4

High-throughput

0.479

High

752924

YHI0
Putative proline--tRNA ligase YHR020W

1

5

High-throughput

0.479

High

757390

IF1A
Eukaryotic translation initiation factor 1A

1

2

High-throughput

0.479

High

796916

VATG
V-type proton ATPase subunit G

1

2

High-throughput

0.479

High

796937

RUVB1
RuvB-like protein 1

1

6

High-throughput

0.479

High

796924

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

7

High-throughput

0.470

High

796947

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.458

High

368167

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.445

High

491579

HSP71
Heat shock protein SSA1

1

7

High-throughput

0.445

High

494252

HSP72
Heat shock protein SSA2

1

7

High-throughput

0.445

High

561248

APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1

1

1

High-throughput

0.445

High

605744

NPR1
Nitrogen permease reactivator protein

1

4

High-throughput

0.445

High

633320

MAS5
Mitochondrial protein import protein MAS5

1

6

High-throughput

0.445

High

667862

MCM5
Minichromosome maintenance protein 5

1

5

High-throughput

0.445

High

694926

HSP7F
Heat shock protein homolog SSE1

1

12

High-throughput

0.445

High

705319

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.445

High

753151

DBP8
ATP-dependent RNA helicase DBP8

1

5

High-throughput

0.445

High

754493

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

768724

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

796920

DBP6
ATP-dependent RNA helicase DBP6

1

2

High-throughput

0.445

High

796944

HRK1
Serine/threonine-protein kinase HRK1

1

2

High-throughput

0.445

High

710777

CASP
Protein CASP

1

4

High-throughput

0.439

High

728707

BDF1
Bromodomain-containing factor 1

1

9

High-throughput

0.439

High

755145

LAM4
Membrane-anchored lipid-binding protein LAM4

1

1

High-throughput

0.439

High

767515

TSC11
Target of rapamycin complex 2 subunit TSC11

1

3

High-throughput

0.439

High

778461

MAD1
Spindle assembly checkpoint component MAD1

1

2

High-throughput

0.439

High

796919

YG3A
Uncharacterized protein YGR130C

1

2

High-throughput

0.439

High

141395

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.437

High

356541

H4
Histone H4

1

1

High-throughput

0.437

High

383210

RL25
Large ribosomal subunit protein uL23

1

3

High-throughput

0.437

High

407130

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.437

High

413575

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.437

High

471119

RS22A
Small ribosomal subunit protein uS8A

1

3

High-throughput

0.437

High

480167

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.437

High

482314

RS18A
Small ribosomal subunit protein uS13A

1

3

High-throughput

0.437

High

524355

CAF20
Cap-associated protein CAF20

1

3

High-throughput

0.437

High

558114

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

606682

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

6

High-throughput

0.437

High

628194

SIS1
Protein SIS1

1

7

High-throughput

0.437

High

629993

BPH1
Beige protein homolog 1

1

3

High-throughput

0.437

High

645512

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.437

High

662540

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

730837

CENPA
Histone H3-like centromeric protein CSE4

1

7

High-throughput

0.437

High

756957

RPN10
26S proteasome regulatory subunit RPN10

1

3

High-throughput

0.437

High

762312

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.437

High

796910

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

5

High-throughput

0.437

High

796915

RS12
Small ribosomal subunit protein eS12

1

4

High-throughput

0.437

High

796927

H3
Histone H3

1

7

High-throughput

0.437

High

796928

NUM1
Nuclear migration protein NUM1

1

4

High-throughput

0.437

High

796930

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.437

High

796932

ESP1
Separin

1

2

High-throughput

0.437

High

796936

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

1

High-throughput

0.437

High

796945

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.437

High

796946

AP3D
AP-3 complex subunit delta

1

3

High-throughput

0.437

High

796955

CMR1
DNA damage-binding protein CMR1

1

2

High-throughput

0.437

High

629341

MSH3
DNA mismatch repair protein MSH3

1

0

High-throughput

0.426

High

796913

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.426

High

520271

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

1

High-throughput

0.407

High

690086

APE2
Aminopeptidase 2, mitochondrial

1

3

High-throughput

0.407

High

762136

YM11
Uncharacterized protein YMR124W

1

1

High-throughput

0.407

High

796914

DPH4
Diphthamide biosynthesis protein 4

1

5

High-throughput

0.407

High

796922

HCH1
Hsp90 co-chaperone HCH1

1

2

High-throughput

0.407

High

796923

CNM67
Chaotic nuclear migration protein 67

1

2

High-throughput

0.407

High

796933

SVL3
Styryl dye vacuolar localization protein 3

1

1

High-throughput

0.407

High

796940

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

2

High-throughput

0.407

High

796941

UBX5
UBX domain-containing protein 5

1

1

High-throughput

0.407

High

796942

SSK1
Osmolarity two-component system protein SSK1

1

2

High-throughput

0.407

High

796949

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.407

High

796952

IES3
Ino eighty subunit 3

1

1

High-throughput

0.407

High

704635

PLSC
1-acyl-sn-glycerol-3-phosphate acyltransferase

2

0

High-throughput

0.307

High

741193

GLYC
Serine hydroxymethyltransferase, cytosolic

2

0

High-throughput

0.307

High

454624

TBA3
Tubulin alpha-3 chain

1

0

High-throughput

0.279

Low

516812

SST2
Protein SST2

1

0

High-throughput

0.279

Low

563966

SEC2
Rab guanine nucleotide exchange factor SEC2

1

0

High-throughput

0.279

Low

730990

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.279

Low

796943

VPS13
Intermembrane lipid transfer protein VPS13

1

0

High-throughput

0.279

Low

753321

EFM1
Protein-lysine N-methyltransferase EFM1

1

0

High-throughput

0.269

Low

690219

CDC3
Cell division control protein 3

1

0

High-throughput

0.251

Low

702675

TYE7
Transcription factor TYE7

1

0

High-throughput

0.251

Low

766489

VAB2
Biogenesis of lysosome-related organelles complex 1 subunit VAB2

1

0

High-throughput

0.251

Low

796917

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.251

Low

796931

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.251

Low

796939

ARR1
Arsenical-resistance protein ARR1

1

0

High-throughput

0.251

Low

745722

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

796938

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

796950

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.249

Low

796951

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.249

Low

606334

SEC15
Exocyst complex component SEC15

1

0

High-throughput

0.232

Low

655133

NAM9
Small ribosomal subunit protein uS4m

1

0

High-throughput

0.232

Low

759193

GDS1
GTPase-GDP dissociation stimulator BEM4

1

0

High-throughput

0.232

Low

765751

PP2C2
Protein phosphatase 2C homolog 2

1

0

High-throughput

0.232

Low

766619

FMP52
Protein FMP52, mitochondrial

1

0

High-throughput

0.232

Low

775048

VHR1
Transcription factor VHR1

1

0

High-throughput

0.232

Low

796912

CDT1
Cell division cycle protein CDT1

1

0

High-throughput

0.232

Low

796918

MDS3
Negative regulator of sporulation MDS3

1

0

High-throughput

0.232

Low

796925

RM22
Large ribosomal subunit protein uL22m

1

0

High-throughput

0.232

Low

796926

SIW14
Inositol phosphatase SIW14

1

0

High-throughput

0.232

Low

796934

FCP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.232

Low

796948

NMD4
Nonsense-mediated decay protein 4

1

0

High-throughput

0.232

Low

796953

ARP7
Actin-related protein 7

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024